Advances of medical nanorobots for future cancer treatments

X Kong, P Gao, J Wang, Y Fang, KC Hwang - Journal of Hematology & …, 2023 - Springer
Early detection and diagnosis of many cancers is very challenging. Late stage detection of a
cancer always leads to high mortality rates. It is imperative to develop novel and more …

Interactions with microbial proteins driving the antibacterial activity of flavonoids

G Donadio, F Mensitieri, V Santoro, V Parisi… - Pharmaceutics, 2021 - mdpi.com
Flavonoids are among the most abundant natural bioactive compounds produced by plants.
Many different activities have been reported for these secondary metabolites against …

Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic development

A Hoermann, T Habtewold, P Selvaraj… - Science …, 2022 - science.org
Gene drives hold promise for the genetic control of malaria vectors. The development of
vector population modification strategies hinges on the availability of effector mechanisms …

PPAR-gamma agonists: Potential modulators of autophagy in obesity

AH Faghfouri, Y Khajebishak, L Payahoo… - European journal of …, 2021 - Elsevier
Autophagy pathways are involved in the pathogenesis of some obesity related health
problems. As obesity is a nutrient sufficiency condition, autophagy process can be altered in …

ATP synthase: a molecular therapeutic drug target for antimicrobial and antitumor peptides

Z Ahmad, F Okafor, S Azim… - Current medicinal …, 2013 - ingentaconnect.com
In this review we discuss the role of ATP synthase as a molecular drug target for natural and
synthetic antimicrobial/antitumor peptides. We start with an introduction of the universal …

Combination effects of baicalein with antibiotics against oral pathogens

EJ Jang, SM Cha, SM Choi, JD Cha - Archives of Oral Biology, 2014 - Elsevier
Background Baicalein is one of the major flavonoids in Scutellaria baicalensis Georgi, which
has long been used in Asia as herbal medicine. Several biological effects of baicalein, such …

Understanding the link between antimicrobial properties of dietary olive phenolics and bacterial ATP synthase

A Amini, M Liu, Z Ahmad - International journal of biological …, 2017 - Elsevier
The naturally occurring olive phenolics tyrosol, hydroxytyrosol, dihydroxyphenylglycol
(DHPG), and oleuropein are known to have antioxidant, antitumor, and antibacterial …

A therapeutic connection between dietary phytochemicals and ATP synthase

Z Ahmad, SS Hassan, S Azim - Current medicinal chemistry, 2017 - ingentaconnect.com
For centuries, phytochemicals have been used to prevent and cure multiple health ailments.
Phytochemicals have been reported to have antioxidant, antidiabetic, antitussive …

A novel RNA aptamer identifies plasma membrane ATP synthase beta subunit as an early marker and therapeutic target in aggressive cancer

S Speransky, P Serafini, J Caroli, S Bicciato… - Breast cancer research …, 2019 - Springer
Purpose Primary breast and prostate cancers can be cured, but metastatic disease cannot.
Identifying cell factors that predict metastatic potential could guide both prognosis and …

Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases

AL Reed, W Mitchell, AT Alexandrescu… - Frontiers in …, 2023 - frontiersin.org
Most mitochondrial proteins are targeted to the organelle by N-terminal mitochondrial
targeting sequences (MTSs, or “presequences”) that are recognized by the import machinery …