DNA repair, recombination, and damage signaling

A Gartner, JA Engebrecht - Genetics, 2022 - academic.oup.com
DNA must be accurately copied and propagated from one cell division to the next, and from
one generation to the next. To ensure the faithful transmission of the genome, a plethora of …

NME/NM23/NDPK and histidine phosphorylation

K Adam, J Ning, J Reina, T Hunter - International journal of molecular …, 2020 - mdpi.com
The NME (Non-metastatic) family members, also known as NDPKs (nucleoside diphosphate
kinases), were originally identified and studied for their nucleoside diphosphate kinase …

Notoginsenoside R1 protects against hypobaric hypoxia-induced high-altitude pulmonary edema by inhibiting apoptosis via ERK1/2-P90rsk-BAD ignaling pathway

C Pei, N Jia, Y Wang, S Zhao, Z Shen, S Shi… - European Journal of …, 2023 - Elsevier
High-altitude pulmonary edema (HAPE) is a potentially fatal disease. Notoginsenoside R1 is
a novel phytoestrogen with anti-inflammatory, antioxidant and anti-apoptosis properties …

Nanopolystyrene-induced microRNAs response in Caenorhabditis elegans after long-term and lose-dose exposure

M Qu, L Luo, Y Yang, Y Kong, D Wang - Science of the Total Environment, 2019 - Elsevier
Abstract microRNAs (miRNAs) usually act post-transcriptionally to suppress the expression
of many targeted genes. However, the response of miRNAs to nanoplastics is still unclear …

Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis

J Lian, X Zhu, J Du, B Huang, F Zhao, C Ma, R Guo… - Molecular Therapy, 2023 - cell.com
Mesenchymal stem cells regulate remote intercellular signaling communication via their
secreted extracellular vesicles. Here, we report that menstrual blood-derived stem cells …

The developmentally timed decay of an essential microRNA family is seed-sequence dependent

BF Donnelly, B Yang, AL Grimme, KF Vieux, CY Liu… - Cell reports, 2022 - cell.com
MicroRNA (miRNA) abundance is tightly controlled by regulation of biogenesis and decay.
Here, we show that the mir-35 miRNA family undergoes selective decay at the transition …

Cerium oxide nanoparticles-carrying human umbilical cord mesenchymal stem cells counteract oxidative damage and facilitate tendon regeneration

X Ren, H Zhuang, Y Zhang, P Zhou - Journal of Nanobiotechnology, 2023 - Springer
Background Tendon injuries have a high incidence and limited treatment options. Stem cell
transplantation is essential for several medical conditions like tendon injuries. However …

Recent advances in understanding microRNA function and regulation in C. elegans

K Kotagama, K McJunkin - Seminars in Cell & Developmental Biology, 2024 - Elsevier
MicroRNAs (miRNAs) were first discovered in C. elegans as essential post-transcriptional
regulators of gene expression. Since their initial discovery, miRNAs have been implicated in …

Regulation of response to nanopolystyrene by intestinal microRNA mir-35 in nematode Caenorhabditis elegans

D Li, Y Yuan, D Wang - Science of the Total Environment, 2020 - Elsevier
In nematode Caenorhabditis elegans, mir-35, a microRNA molecule, was involved in the
control of response to nanopolystyrene. Exposure to nanopolystyrene (100 nm) could …

Prolonged exposure to multi-walled carbon nanotubes dysregulates intestinal mir-35 and its direct target MAB-3 in nematode Caenorhabditis elegans

Y Zhao, L Jin, Y Wang, Y Kong, D Wang - Scientific Reports, 2019 - nature.com
In nematode Caenorhabditis elegans, some microRNAs (miRNAs) could be dysregulated by
multi-walled carbon nanotubes (MWCNTs), suggesting their involvement in regulating the …