A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

Biomarkers of platinum resistance in ovarian cancer: what can we use to improve treatment

B van Zyl, D Tang, NA Bowden - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Ovarian cancer has poor survival rates due to a combination of diagnosis at advanced
disease stages and disease recurrence as a result of platinum chemotherapy resistance …

MicroRNA therapeutics: the next magic bullet?

B Simonson, S Das - Mini reviews in medicinal chemistry, 2015 - ingentaconnect.com
MicroRNAs are short noncoding 18-25 nucleotide long RNA which bind and inhibit mRNA.
Currently, there are over 1000 known human microRNAs, and microRNAs control over 50 …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

MicroRNA in glioblastoma: an overview

B Banelli, A Forlani, G Allemanni… - … journal of genomics, 2017 - Wiley Online Library
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal
therapy, is an invariably lethal cancer with a life expectancy that depends on the tumor …

Roles of non-coding RNAs and angiogenesis in glioblastoma

E Balandeh, K Mohammadshafie… - Frontiers in cell and …, 2021 - frontiersin.org
One of the significant hallmarks of cancer is angiogenesis. It has a crucial function in tumor
development and metastasis. Thus, angiogenesis has become one of the most exciting …

miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study

BN Hannafon, A Cai, CL Calloway, YF Xu, R Zhang… - BMC cancer, 2019 - Springer
Background Altered expression of microRNAs (miRNAs) is known to contribute to cancer
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …

[HTML][HTML] Role of microRNAs in glioblastoma

M Chen, Z Medarova, A Moore - Oncotarget, 2021 - ncbi.nlm.nih.gov
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …

MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention

C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …