Restoration of coronary microvascular function by OGA overexpression in a high-fat diet with low-dose streptozotocin-induced type 2 diabetic mice
JT Cabrera, R Si, A Tsuji-Hosokawa… - Diabetes and …, 2023 - journals.sagepub.com
Sustained hyperglycemia results in excess protein O-GlcNAcylation, leading to vascular
complications in diabetes. This study aims to investigate the role of O-GlcNAcylation in the …
complications in diabetes. This study aims to investigate the role of O-GlcNAcylation in the …
Endothelial dysfunction and coronary vasoreactivity-a review of the history, physiology, diagnostic techniques, and clinical relevance
T Gunawardena, I Merinopoulos… - Current Cardiology …, 2021 - ingentaconnect.com
The fervency for advancement and evolution in percutaneous coronary intervention has
revolutionised the treatment of coronary artery disease. Historically, the focus of the …
revolutionised the treatment of coronary artery disease. Historically, the focus of the …
Overexpression of p53 due to excess protein O-GlcNAcylation is associated with coronary microvascular disease in type 2 diabetes
R Si, Q Zhang, A Tsuji-Hosokawa… - Cardiovascular …, 2020 - academic.oup.com
Aims We previously reported that increased protein O-GlcNAcylation in diabetic mice led to
vascular rarefaction in the heart. In this study, we aimed to investigate whether and how …
vascular rarefaction in the heart. In this study, we aimed to investigate whether and how …
[HTML][HTML] Enhanced antioxidative defense by vitamins C and E consumption prevents 7-day high-salt diet-induced microvascular endothelial function impairment in …
This study aimed to examine whether the oral supplementation of vitamins C and E during a
seven-day high salt diet (HS;~ 14 g salt/day) prevents microvascular endothelial function …
seven-day high salt diet (HS;~ 14 g salt/day) prevents microvascular endothelial function …
Single-cell RNA sequencing: in-depth decoding of heart biology and cardiovascular diseases
Z Chen, L Wei, F Duru, L Chen - Current genomics, 2020 - ingentaconnect.com
Background: The cardiac system is a combination of a complex structure, various cells, and
versatile specified functions and sophisticated regulatory mechanisms. Moreover, cardiac …
versatile specified functions and sophisticated regulatory mechanisms. Moreover, cardiac …
[HTML][HTML] Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice
M Pan, Y Han, A Basu, A Dai, R Si… - … of Physiology-Cell …, 2018 - journals.physiology.org
Coronary microvascular rarefaction, due to endothelial cell (EC) dysfunction, is one of the
causes of increased morbidity and mortality in diabetes. Coronary ECs in diabetes are more …
causes of increased morbidity and mortality in diabetes. Coronary ECs in diabetes are more …
Hypotension in hereditary cardiomyopathy
J Al-Khoury, D Jacques, G Bkaily - Pflügers Archiv-European Journal of …, 2022 - Springer
It is well accepted that hypertension may lead to the development of heart failure (HF).
However, little is known about the development of hypotension that may contribute to the …
However, little is known about the development of hypotension that may contribute to the …
The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases,
especially associated with the aging of the world population. During aging, the progressive …
especially associated with the aging of the world population. During aging, the progressive …
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction
J Zhang, H Li, D Wang, J Gu, Y Hou… - Drug Design …, 2023 - Taylor & Francis
Purpose The aim of our study was to investigate the mechanism by which the Chinese
compound Shensong Yangxin Capsule (SSYX) reduces susceptibility to arrhythmia in db/db …
compound Shensong Yangxin Capsule (SSYX) reduces susceptibility to arrhythmia in db/db …
Shexiang Tongxin dropping pill (麝香通心滴丸) protects against sodium laurate-induced coronary microcirculatory dysfunction in rats.
LIU Huahua, Z Jingjing, PAN Sunlei… - Journal of …, 2021 - search.ebscohost.com
OBJECTIVE: To investigate the protective effects of Shexiang Tongxin dropping pill
(麝香通心滴丸, STDP) in a rat model of coronary microcirculatory dysfunction (CMD) …
(麝香通心滴丸, STDP) in a rat model of coronary microcirculatory dysfunction (CMD) …