Histamine, neuroinflammation and neurodevelopment: a review

E Carthy, T Ellender - Frontiers in neuroscience, 2021 - frontiersin.org
The biogenic amine, histamine, has been shown to critically modulate inflammatory
processes as well as the properties of neurons and synapses in the brain, and is also …

[HTML][HTML] Changes in histaminergic system in neuropsychiatric disorders and the potential treatment consequences

L Shan, DF Swaab - Current neuropharmacology, 2022 - ncbi.nlm.nih.gov
In contrast to that of other monoamine neurotransmitters, the association of the histaminergic
system with neuropsychiatric disorders is not well documented. In the last two decades …

Generation and propagation of bursts of activity in the developing basal ganglia

S Klavinskis-Whiting, S Bitzenhofer… - Cerebral …, 2023 - academic.oup.com
The neonatal brain is characterized by intermittent bursts of oscillatory activity interspersed
by relative silence. Although well-characterized for many cortical areas, to what extent these …

The Effects of Ceftriaxone on Glutamate Transporter Expression and the Gut Microbiome: Implications for a Role of Antibiotic-Induced Dysbiosis in Mediating Drug …

AD Winters, DM Francescutti, DJ Kracht… - Gut Microbes …, 2024 - Taylor & Francis
ABSTRACT Ceftriaxone (CTX), a beta-lactam antibiotic, is widely used in drug seeking and
relapse studies due to its ability to enhance glutamate transporter (GLT-1) expression in the …

Central histaminergic signalling, neural excitability and epilepsy

L Yang, Y Wang, Z Chen - British Journal of Pharmacology, 2022 - Wiley Online Library
Epilepsy is a common neurological disorder characterized by repeated and spontaneous
epileptic seizures and is not well controlled by current medication. Traditional theory …

Gastrin-releasing peptide signaling in the nucleus accumbens medial shell regulates neuronal excitability and motivation

EE Aisenberg, TL Li, H Wang, AA Sahagun, EM Tu… - bioRxiv, 2024 - biorxiv.org
Neuropeptides are the largest class of neuromodulators. It has been shown that
subpopulations of dopamine neurons express mRNA for the neuropeptide Gastrin-releasing …

Working memory processes and the histamine-3 receptor in schizophrenia: a [11C]MK-8278 PET-fMRI study

A Arumuham, E Shatalina, MM Nour, M Veronese… - …, 2024 - Springer
Rationale Working memory impairment is a prominent feature of schizophrenia which
predicts clinical and functional outcomes. Preclinical data suggest histamine-3 receptor …

[HTML][HTML] Histaminergic System Activity in the Central Nervous System: The Role in Neurodevelopmental and Neurodegenerative Disorders

D Szukiewicz - International Journal of Molecular Sciences, 2024 - mdpi.com
Histamine (HA), a biogenic monoamine, exerts its pleiotropic effects through four H1R–H4R
histamine receptors, which are also expressed in brain tissue. Together with the projections …

Inhibition of histamine receptor 3 alleviates sevoflurane-induced hypomyelination and neurobehavioral deficits

J Che, Y Wu, J Dong, X Jiang, L Yang, Y Chen… - Experimental …, 2025 - Elsevier
Background Inhalational anesthetic sevoflurane can cause myelination damage in
developing brain. This study examines the effects of histamine receptor 3 (H3) antagonist …

Generation and propagation of network bursts in the basal ganglia exhibit dynamic changes during early postnatal development

S Klavinskis-Whiting, S Bitzenhofer, I Hanganu-Opatz… - bioRxiv, 2022 - biorxiv.org
The neonatal brain is characterised by intermittent bursts of oscillatory activity interspersed
by relative silence. While these bursts of activity are well characterised for many cortical …