VDAC, a multi-functional mitochondrial protein regulating cell life and death

V Shoshan-Barmatz, V De Pinto, M Zweckstetter… - Molecular aspects of …, 2010 - Elsevier
Research over the past decade has extended the prevailing view of the mitochondrion to
include functions well beyond the generation of cellular energy. It is now recognized that …

The mitochondrial permeability transition

M Zoratti, I Szabò - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1995 - Elsevier
This review deals with the permeability transition (PT) of isolated mitochondria, a field
spawned at the very beginning of mitochondrial research by the observation that the …

[HTML][HTML] Mitochondrial channels: ion fluxes and more

I Szabo, M Zoratti - Physiological reviews, 2014 - journals.physiology.org
The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Permeation of hydrophilic solutes through mitochondrial outer membranes: review on mitochondrial porins

R Benz - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1994 - Elsevier
The mitochondrial outer membrane acts as a molecular filter for hydrophilic solutes since it is
freely permeable to a variety of small hydrophilic solutes, but retains molecules with higher …

[HTML][HTML] VDAC isoforms in mammals

A Messina, S Reina, F Guarino, V De Pinto - Biochimica et Biophysica Acta …, 2012 - Elsevier
VDACs (Voltage Dependent Anion selective Channels) are a family of pore-forming proteins
discovered in the mitochondrial outer membrane. In the animal kingdom, mammals show a …

[HTML][HTML] VDAC in cancer

NM Mazure - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2017 - Elsevier
The voltage-dependent anion channel (VDAC) is a pore located at the outer membrane of
the mitochondrion. It allows the entry and exit of numerous ions and metabolites between …

Ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC)

G Báthori, G Csordás, C Garcia-Perez, E Davies… - Journal of Biological …, 2006 - ASBMB
Cell function depends on the distribution of cytosolic and mitochondrial factors across the
outer mitochondrial membrane (OMM). Passage of metabolites through the OMM has been …

[HTML][HTML] Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

E Blachly-Dyson, EB Zambronicz, WH Yu… - Journal of Biological …, 1993 - Elsevier
The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane is a
small abundant protein found in all eukaryotic kingdoms which forms a voltage-gated pore …

[HTML][HTML] Characterization of human VDAC isoforms: a peculiar function for VDAC3?

V De Pinto, F Guarino, A Guarnera, A Messina… - … et Biophysica Acta (BBA …, 2010 - Elsevier
VDACs are a family of pore-forming proteins mainly located in the mitochondrial outer
membrane. In mammals three isoforms exist. In this work we review the information …

Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for β-oxidation and glycerolipid synthesis

JT Rasmussen, NJ Færgeman, K Kristiansen… - Biochemical …, 1994 - portlandpress.com
The dissociation constants for octanoyl-CoA, dodecanoyl-CoA and hexadecanoyl-CoA
binding to acyl-CoA-binding protein (ACBP) were determined by using titration …