An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection

S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …

MAFLD: A multisystem disease

RM Pipitone, C Ciccioli, G Infantino… - Therapeutic …, 2023 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

ROS-scavenging therapeutic hydrogels for modulation of the inflammatory response

YE Kim, J Kim - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

[HTML][HTML] Mitochondrial dysfunction in neurodegenerative disorders

MM Klemmensen, SH Borrowman, C Pearce, B Pyles… - …, 2024 - Elsevier
Recent advances in understanding the role of mitochondrial dysfunction in
neurodegenerative diseases have expanded the opportunities for neurotherapeutics …

Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function

BL Tan, ME Norhaizan - Nutrients, 2019 - mdpi.com
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease

Y Ma, G Lee, SY Heo, YS Roh - Antioxidants, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response

NA Snyder, GM Silva - Journal of Biological Chemistry, 2021 - ASBMB
Ubiquitin signaling is a conserved, widespread, and dynamic process in which protein
substrates are rapidly modified by ubiquitin to impact protein activity, localization, or stability …

Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases

Y Fan, Z Chen, M Zhang - Journal of Translational Medicine, 2022 - Springer
Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …