This review article will consider the preparation and application of ynones in synthetic
organic chemistry. Concerning the preparation of these bifunctional compounds, several …

Several novel oxygenated polyunsaturated lipid mediators biosynthesized from n-3
docosapentaenoic acid were recently isolated from murine inflammatory exudates and …

The polyunsaturated lipid mediator PD1n-3 DPA (5) was recently isolated from self-resolving
inflammatory exudates of 5 and human macrophages. Herein, the first total synthesis of …

Practical and highly efficient methods for oxidative rearrangement of tertiary allylic alcohols
to β-substituted α, β-unsaturated carbonyl compounds employing oxoammonium salts are …

The first total synthesis of the lipid mediator MaR1n− 3 DPA (5) has been achieved in 12%
overall yield over 11 steps. The stereoselective preparation of 5 was based on a Pd …

A convergent stereoselective synthesis of the potent anti-inflammatory, proresolving and
neuroprotective lipid mediator protectin D1 (2) has been achieved in 15% yield over eight …

The resolution of inflammation is a biosynthetically active process controlled by the interplay
between oxygenated polyunsaturated mediators and G-protein coupled receptor-signaling …

Protectin D1 (PD1 (3)), a C22-dihydroxylated polyunsaturated fatty acid biosynthesized from
all-Z-docosahexaenoic acid, belongs to the new family of endogenous mediators referred to …

Maresin 1 is a potent anti-inflammatory and pro-resolving lipid mediator derived from
docosahexaenoic acid. The total synthesis of maresin 1 is achieved in 10 steps and in 7 …

The novel catalytic method for the oxidative rearrangement of tertiary allylic alcohols to β-
substituted α, β-unsaturated ketones is described. TEMPO/NaIO4− SiO2 causes facile and …