Transcriptional responses to ppGpp and DksA
RL Gourse, AY Chen, S Gopalkrishnan… - Annual review of …, 2018 - annualreviews.org
The stringent response to nutrient deprivation is a stress response found throughout the
bacterial domain of life. Although first described in proteobacteria for matching ribosome …
bacterial domain of life. Although first described in proteobacteria for matching ribosome …
rRNA Transcription in Escherichia coli
▪ Abstract Ribosomal RNA transcription is the rate-limiting step in ribosome synthesis in
bacteria and has been investigated intensely for over half a century. Multiple mechanisms …
bacteria and has been investigated intensely for over half a century. Multiple mechanisms …
Genome-wide effects on Escherichia coli transcription from ppGpp binding to its two sites on RNA polymerase
P Sanchez-Vazquez, CN Dewey… - Proceedings of the …, 2019 - National Acad Sciences
The second messenger nucleotide ppGpp dramatically alters gene expression in bacteria to
adjust cellular metabolism to nutrient availability. ppGpp binds to two sites on RNA …
adjust cellular metabolism to nutrient availability. ppGpp binds to two sites on RNA …
[HTML][HTML] DksA: a critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP
BJ Paul, MM Barker, W Ross, DA Schneider, C Webb… - Cell, 2004 - cell.com
Ribosomal RNA (rRNA) transcription is regulated primarily at the level of initiation from rRNA
promoters. The unusual kinetic properties of these promoters result in their specific …
promoters. The unusual kinetic properties of these promoters result in their specific …
DksA potentiates direct activation of amino acid promoters by ppGpp
BJ Paul, MB Berkmen… - Proceedings of the …, 2005 - National Acad Sciences
Amino acid starvation in Escherichia coli results in a spectrum of changes in gene
expression, including inhibition of rRNA and tRNA promoters and activation of certain …
expression, including inhibition of rRNA and tRNA promoters and activation of certain …
An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulation
As an approach to the study of rRNA synthesis in Gram‐positive bacteria, we characterized
the regulation of the Bacillus subtilis rrnB and rrnO rRNA promoters. We conclude that B …
the regulation of the Bacillus subtilis rrnB and rrnO rRNA promoters. We conclude that B …
Physiology of mycobacteria
Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial …
achieved a spread in the human population that is unmatched by any other bacterial …
[HTML][HTML] rRNA promoter regulation by nonoptimal binding of σ region 1.2: an additional recognition element for RNA polymerase
Regulation of transcription initiation is generally attributable to activator/repressor proteins
that bind to specific DNA sequences. However, regulators can also achieve specificity by …
that bind to specific DNA sequences. However, regulators can also achieve specificity by …
6S RNA function enhances long-term cell survival
AE Trotochaud, KM Wassarman - Journal of bacteriology, 2004 - Am Soc Microbiol
ABSTRACT 6S RNA was identified in Escherichia coli> 30 years ago, but the physiological
role of this RNA has remained elusive. Here, we demonstrate that 6S RNA-deficient cells are …
role of this RNA has remained elusive. Here, we demonstrate that 6S RNA-deficient cells are …
rRNA Promoter Activity in the Fast-Growing Bacterium Vibrio natriegens
The bacterium Vibrio natriegens can double with a generation time of less than 10 min (RG
Eagon, J. Bacteriol. 83: 736-737, 1962), a growth rate that requires an extremely high rate of …
Eagon, J. Bacteriol. 83: 736-737, 1962), a growth rate that requires an extremely high rate of …