Could SARS-CoV-2 spike protein be responsible for long-COVID syndrome?

TC Theoharides - Molecular Neurobiology, 2022 - Springer
SARS-CoV-2 infects cells via its spike protein binding to its surface receptor on target cells
and results in acute symptoms involving especially the lungs known as COVID-19. However …

Infection mechanism of SARS-COV-2 and its implication on the nervous system

EE Reza-Zaldívar, MA Hernández-Sapiéns… - Frontiers in …, 2021 - frontiersin.org
In late December 2019, multiple atypical pneumonia cases resulted in severe acute
respiratory syndrome caused by a pathogen identified as a novel coronavirus SARS-CoV-2 …

Omicron (BA. 1) and sub‐variants (BA. 1.1, BA. 2, and BA. 3) of SARS‐CoV‐2 spike infectivity and pathogenicity: A comparative sequence and structural‐based …

S Kumar, K Karuppanan… - Journal of medical …, 2022 - Wiley Online Library
The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has now spread throughout the world. We used computational tools to assess the spike …

[HTML][HTML] The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

EM Rhea, AF Logsdon, KM Hansen, LM Williams… - Nature …, 2021 - nature.com
It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …

Rapid and efficient detection of the SARS-CoV-2 spike protein using an electrochemical aptamer-based sensor

A Idili, C Parolo, R Alvarez-Diduk, A Merkoçi - ACS sensors, 2021 - ACS Publications
The availability of sensors able to rapidly detect SARS-CoV-2 directly in biological fluids in a
single step would allow performing massive diagnostic testing to track in real time and …

Aptamer-based electrochemical biosensor for rapid detection of SARS-CoV-2: Nanoscale electrode-aptamer-SARS-CoV-2 imaging by photo-induced force …

JC Abrego-Martinez, M Jafari, S Chergui… - Biosensors and …, 2022 - Elsevier
Rapid, mass diagnosis of the coronavirus disease 2019 (COVID-19) is critical to stop the
ongoing infection spread. The two standard screening methods to confirm the severe acute …

SARS-CoV-2 detection with aptamer-functionalized gold nanoparticles

S Aithal, S Mishriki, R Gupta, RP Sahu, G Botos… - Talanta, 2022 - Elsevier
A rapid detection test for SARS-CoV-2 is urgently required to monitor virus spread and
containment. Here, we describe a test that uses nanoprobes, which are gold nanoparticles …

Neurotropism of SARS-CoV-2 and neurological diseases of the central nervous system in COVID-19 patients

S Veleri - Experimental brain research, 2022 - Springer
The devastating COVID-19 pandemic is caused by the SARS-CoV-2 virus. It primarily affects
the lung and induces acute respiratory distress leading to a decrease in oxygen supply to …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

[HTML][HTML] SARS-CoV-2 spike protein induces hemagglutination: implications for COVID-19 morbidities and therapeutics and for vaccine adverse effects

C Boschi, DE Scheim, A Bancod, M Militello… - International Journal of …, 2022 - mdpi.com
Experimental findings for SARS-CoV-2 related to the glycan biochemistry of coronaviruses
indicate that attachments from spike protein to glycoconjugates on the surfaces of red blood …