BACKGROUND: Each year approximately 10million babies do not breathe immediately at
birth, of which about 6million require basic neonatal resuscitation. The major burden is in …

Perinatal cerebral hypoxia–ischemia remains a frequent cause of the chronic handicapping
conditions of cerebral palsy, mental retardation, learning disability, and epilepsy. 1 …

An extensive literature demonstrates that glucocorticoids (GCs), the adrenal steroids
secreted during stress, can have a broad range of deleterious effects in the brain. The …

Hypoxia threatens brain function during the entire life-span starting from early fetal age up to
senescence. This review compares the short-term, long-term and life-spanning effects of …

Perinatal brain damage in the mature fetus is usually brought about by severe intrauterine
asphyxia following an acute reduction of the uterine or umbilical circulation. The areas most …

Perinatal brain damage in the mature fetus is usually brought about by severe intrauterine
asphyxia following an acute reduction of the uterine or umbilical circulation. The areas most …

The preterm newborn is at significant risk of neural injury and impaired neurodevelopment.
Infants with mild or no evidence of injury may also be at risk of altered brain development …

The occurrence of hypoxia–ischemia (HI) during early fetal or neonatal stages of an
individual leads to the damaging of immature neurons resulting in behavioral and …

Cerebral vascular diseases, such as neonatal encephalopathy and focal or global cerebral
ischemia, all result in reduction of blood flow to the affected regions, and cause hypoxia …

We critically evaluated various design features from 292 animal studies related to perinatal
hypoxic-ischemic encephalopathy (HIE). Rodents were the most frequently used animals in …