Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

Endothelial dysfunction in neurodegenerative diseases

YC Fang, YC Hsieh, CJ Hu, YK Tu - International journal of molecular …, 2023 - mdpi.com
The cerebral vascular system stringently regulates cerebral blood flow (CBF). The
components of the blood–brain barrier (BBB) protect the brain from pathogenic infections …

Editorial of special issue 'dissecting neurological and neuropsychiatric diseases: Neurodegeneration and neuroprotection'

M Tanaka, L Vécsei - International journal of molecular sciences, 2022 - mdpi.com
This Special Issue has focused on dissecting the neuroprotective and neurodegenerative
components of neurological and neuropsychiatric diseases, highlighting the latest advance …

[HTML][HTML] Preclinical modeling in depression and anxiety: Current challenges and future research directions

M Tanaka, Á Szabó, L Vécsei - Advances in Clinical and …, 2023 - advances.umw.edu.pl
This editorial highlights the limitations of preclinical models in accurately reflecting the
complexity of anxiety and depression, which leads to a lack of effective treatments for these …

The heterogeneity of late-life depression and its pathobiology: a brain network dysfunction disorder

KA Jellinger - Journal of Neural Transmission, 2023 - Springer
Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …

The associations of neutrophil–lymphocyte, platelet–lymphocyte, monocyte–lymphocyte ratios and immune-inflammation index with negative symptoms in patients …

M Šagud, Z Madžarac, G Nedic Erjavec… - Biomolecules, 2023 - mdpi.com
Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), monocyte–lymphocyte
ratio (MLR) and systemic immune-inflammation index (SII index) are increasingly used as …

Exercise for mental well-being: exploring Neurobiological advances and intervention effects in depression

J Ren, H Xiao - Life, 2023 - mdpi.com
Depression is a common mental disorder in which patients often experience feelings of
sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for …

[HTML][HTML] Recent advances in the study of the neurobiological mechanisms behind the effects of physical activity on mood, resilience and emotional disorders

C Chen, S Nakagawa - Advances in Clinical and …, 2023 - advances.umw.edu.pl
Physical activity (PA) significantly influences emotional wellbeing, from enhancing mood to
counteracting emotional disorders such as depression and anxiety. This article offers an in …

Antidepressant effect of intermittent long-term systemic administration of irisin in mice

P Pignataro, M Dicarlo, R Zerlotin, G Storlino… - International Journal of …, 2022 - mdpi.com
Depression is a psychiatric disorder increasingly diffused worldwide. Evidence suggests that
irisin, a myokine secreted by contracting muscle, mediates beneficial effects on several …

The relationship between stress, inflammation, and depression

IB Kim, JH Lee, SC Park - Biomedicines, 2022 - mdpi.com
A narrative review about the relationship between stress, inflammation, and depression is
made as follows: Chronic stress leads to various stress-related diseases such as …