Recent advancements in Irinotecan-loaded nanomaterials as a smart drug delivery system for cancer therapy: A state-of-art-review

S Fathi-Karkan, M Qindeel, R Arshad, Z Moafian… - Inorganic Chemistry …, 2024 - Elsevier
The convergence of nanotechnology and medicine has filled a large gap in therapeutic
strategies, improving cancer treatment drastically. In this review paper, current …

Folate-Modified pH and ROS Dual-Responsive Polymeric Nanocarriers for Targeted Anticancer Drug Delivery

F Dai, F Chen, J Zhang, X Chen, H Liang… - ACS Applied Nano …, 2024 - ACS Publications
The tumor microenvironment is distinguished from normal tissues, such as the acidic
microenvironment, elevated reactive oxygen species (ROS) levels, and overexpressed …

Oral delivery of solid lipid nanoparticles surface decorated with hyaluronic acid and bovine serum albumin: A novel approach to treat colon cancer through active …

SS Ahmed, MZ Baba, U Wahedi, J Koppula… - International Journal of …, 2024 - Elsevier
The present study aims to prepare and evaluate solid lipid nanoparticles (SLNs) loaded with
irinotecan (IRN) drug and daidzein (DZN) isoflavonoid and surface coated with ligand …

Folate receptor-mediated delivery system based on chitosan coated polymeric nanoparticles for combination therapy of breast cancer

S Jamali, B Jamali, F Abedi, M Firoozrai… - Journal of …, 2024 - Taylor & Francis
Combination therapy using two or more drugs with different mechanisms of action is an
effective strategy for treating cancer. This is because of the synergistic effect of …

Tailored design of pH-responsive microbeads for oral delivery of lactoferrin nanotherapeutics of colon cancer

DG Zayed, SN Khattab, L Heikal, M Teleb… - Journal of Drug Delivery …, 2024 - Elsevier
Colorectal cancer, one of the most fatal cancer types, has an unmet need for the
development of targeted oral therapeutics. To address this, we propose to engineer a …

Fabrication of etoposide-loaded folic-acid-clocked mesoporous nanoparticles: Investigation of lung cancer proliferation and induction of apoptosis and ferroptosis

W Chen, X Cao, S Wu, Y Huang - Process Biochemistry, 2024 - Elsevier
Etoposide (EPT) offers significant benefits in the tumor therapy domain. EPT may cause
ferroptosis in lung cancer cells; however, its limited bioavailability and low water solubility …