The microbiome is undoubtedly the second genome of the human body and has diverse
roles in health and disease. However, translational progress is limited due to the vastness of …

Incidences of breast, colorectal and prostate cancer are high in the Western world compared
to countries in Asia. We have postulated that the Western diet compared to the …

The importance of estrogens in homeostatic regulation of many cellular and biochemical
events is well illustrated by the pathophysiologic changes that occur with estrogen …

Information concerning the fundamental mechanisms of action of both natural and
environmental hormones, combined with information concerning endogenous hormone …

This review focuses on the possible role in human health of the consumption of lignan-rich
foods. Most of the plant lignans in human foods are converted by the intestinal microflora in …

Flaxseed is the richest source of the lignan secoisolariciresinol diglucoside (SDG). After
ingestion, SDG is converted to secoisolariciresinol, which is further metabolised to the …

We have developed a relative binding affinity-serum modified access (RBA-SMA) assay to
determine the effect of serum on the access of xenoestrogens to estrogen receptors within …

Epidemiologic studies revealed low mortality in hormone-dependent cancer in Japanese
women and men consuming a traditional diet. We previously found that certain diphenolic …

Purpose: Flaxseed, the richest source of mammalian lignan precursors, has previously been
shown to reduce the growth of tumors in rats. This study examined, in a randomized double …

Experimental and epidemiologic studies support the view that soyfoods prevent cancer as
well as diseases and symptoms associated with estrogen deficiency. Recent research …