Dengue is the most common arboviral disease caused by one of four distinct but closely
related dengue viruses (DENV) and places significant economic and public health burdens …

The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

Dengue virus (DENV) induces strong T and B cell responses upon infection. Hence, it is
difficult to determine the contribution of cell-mediated immunity alone in the long lasting …

Dengue is one of the most frequently transmitted mosquito-borne diseases in the world,
which creates a significant public health concern globally, especially in tropical and …

Recombinant proteins are gaining enormous importance these days due to their wide
application as biopharmaceutical products and proven safety record. Various recombinant …

Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a
structural protein of flavivirus, is dimeric and alpha-helical, with several special structural …

Despite the rapid development of vaccines against COVID-19, they have important
limitations, such as safety issues, the scope of their efficacy, and the induction of mucosal …

The genus flavivirus of the Flaviridae family includes several human pathogens, like
dengue, Zika, Japanese encephalitis, and yellow fever virus. These viruses continue to be a …

Declining levels of maternal antibodies were shown to sensitize infants born to dengue-
immune mothers to severe disease during primary infection, through the process of antibody …

Dengue is one of the most important diseases transmitted by mosquitoes. Dengvaxia®, a
vaccine registered in several countries, cannot be administered to non-immune individuals …