Psychedelics
DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …
perception and mood and affect numerous cognitive processes. They are generally …
Fifty years on: Serotonin and depression
It has been over 50 years since the original serotonin hypothesis was proposed by the
British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the …
British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the …
[HTML][HTML] Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors
The serotonin system modulates a wide variety of emotional behaviors and states, including
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
[HTML][HTML] Anatomically defined and functionally distinct dorsal raphe serotonin sub-systems
The dorsal raphe (DR) constitutes a major serotonergic input to the forebrain and modulates
diverse functions and brain states, including mood, anxiety, and sensory and motor …
diverse functions and brain states, including mood, anxiety, and sensory and motor …
A high-resolution in vivo atlas of the human brain's serotonin system
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
[HTML][HTML] The serotonergic raphe promote sleep in zebrafish and mice
G Oikonomou, M Altermatt, R Zhang, GM Coughlin… - Neuron, 2019 - cell.com
The role of serotonin (5-HT) in sleep is controversial: early studies suggested a sleep-
promoting role, but eventually the paradigm shifted toward a wake-promoting function for the …
promoting role, but eventually the paradigm shifted toward a wake-promoting function for the …
[HTML][HTML] Presynaptic partners of dorsal raphe serotonergic and GABAergic neurons
B Weissbourd, J Ren, KE DeLoach, CJ Guenthner… - Neuron, 2014 - cell.com
The serotonin system powerfully modulates physiology and behavior in health and disease,
yet the circuit mechanisms underlying serotonin neuron activity are poorly understood. The …
yet the circuit mechanisms underlying serotonin neuron activity are poorly understood. The …
Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system
Dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT), and endocannabinoids (ECs) are
key neuromodulators involved in many aspects of motivated behavior, including reward …
key neuromodulators involved in many aspects of motivated behavior, including reward …
Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens
AL Halberstadt, MA Geyer - Neuropharmacology, 2011 - Elsevier
Serotonergic hallucinogens produce profound changes in perception, mood, and cognition.
These drugs include phenylalkylamines such as mescaline and 2, 5-dimethoxy-4 …
These drugs include phenylalkylamines such as mescaline and 2, 5-dimethoxy-4 …
Drugs as instruments: a new framework for non-addictive psychoactive drug use
CP Müller, G Schumann - Behavioral and Brain Sciences, 2011 - cambridge.org
Most people who are regular consumers of psychoactive drugs are not drug addicts, nor will
they ever become addicts. In neurobiological theories, non-addictive drug consumption is …
they ever become addicts. In neurobiological theories, non-addictive drug consumption is …