During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …

BACKGROUND Preimplantation genetic testing (PGT) encompasses methods that allow
embryos to be tested for severe inherited conditions or for chromosome abnormalities …

Preimplantation genetic screening (PGS) is widely used to select in vitro-fertilized embryos
free of chromosomal abnormalities and to improve the clinical outcome of in vitro fertilization …

There is a high incidence of chromosomal abnormalities in early human embryos, whether
they are generated by natural conception or by assisted reproductive technologies (ART) …

Background: Preimplantation genetic testing (PGT) is widely used today in in-vitro
fertilization (IVF) centers over the world for selecting euploid embryos for transfer and to …

Objective To investigate the presence of DNA in blastocyst fluids (BFs) and to estimate
whether the chromosomal status predicted by its analysis corresponds with the ploidy …

Objective To characterize nuclear and mitochondrial DNA (mtDNA) in spent culture media
from normally developing blastocysts to determine whether it could be used for noninvasive …

Objective To assess whether embryonic DNA isolated from blastocyst culture conditioned
medium (BCCM) combined with blastocoel fluid (BF) could be used for blastocyst stage non …

In this study, for the first time, we demonstrated the presence of microRNAs and extracellular
vesicles in human blastocoel fluid. The bioinformatic and comparative analyses identified …

STUDY QUESTION Is minimally invasive chromosome screening (MICS) using blastocyst
culture medium (BCM) sufficiently fast and accurate for preimplantation genetic testing (PGT) …