Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare,
inherited cholestatic liver disorders that manifest in infants and children and are associated …

Chronic liver disease incidence is increasing among children worldwide due to a multitude
of epidemiological changes. Most of these chronic insults to the pediatric liver progress to …

Background & Aims Data on the management of primary sclerosing cholangitis (PSC) in
European expert centres are sparse. In this study, a PSC group from the ERN RARE-LIVER …

Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of
inflammatory bowel disease (IBD) and a lead indication for liver transplantation (LT) in the …

Objectives: Anti-neutrophil cytoplasmic antibody (ANCA) directed against proteinase 3
(PR3) is a marker for granulomatosis with polyangiitis, but is also found in patients with …

Chronic hepatitis is defined as elevation of liver aminotransferases over a sustained period
of time and is often associated with hepatic inflammation and fibrosis. The differential …

Objectives: Most patients with primary sclerosing cholangitis (PSC) also have inflammatory
bowel disease (IBD). The liver and colon express MAdCAM‐1, a target of lymphocyte …

Primary sclerosing cholangitis (PSC) is a rare, progressive liver disease characterized by
cholestasis and bile duct fibrosis that has no accepted therapy known to delay or arrest its …

Prevalence of inflammatory bowel disease has been on the rise in recent years, especially
in pediatric populations. This study aimed to provide precise identification and stratification …