[HTML][HTML] PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

MA Kappes, KS Faaberg - Virology, 2015 - Elsevier
Porcine reproductive and respiratory disease virus (PRRSV) has the intrinsic ability to adapt
and evolve. After 25 years of study, this persistent pathogen has continued to frustrate efforts …

Arterivirus molecular biology and pathogenesis

EJ Snijder, M Kikkert, Y Fang - Journal of General …, 2013 - microbiologyresearch.org
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

Porcine reproductive and respiratory disease virus: Evolution and recombination yields distinct ORF5 RFLP 1-7-4 viruses with individual pathogenicity

AGM van Geelen, TK Anderson, KM Lager, PB Das… - Virology, 2018 - Elsevier
Recent cases of porcine reproductive and respiratory syndrome virus (PRRSV) infection in
United States swine-herds have been associated with high mortality in piglets and severe …

In-Depth Bioinformatic Analyses of Nidovirales Including Human SARS-CoV-2, SARS-CoV, MERS-CoV Viruses Suggest Important Roles of Non-canonical Nucleic …

M Bartas, V Brázda, N Bohálová, A Cantara… - Frontiers in …, 2020 - frontiersin.org
Non-canonical nucleic acid structures play important roles in the regulation of molecular
processes. Considering the importance of the ongoing coronavirus crisis, we decided to …

Two residues in NSP9 contribute to the enhanced replication and pathogenicity of highly pathogenic porcine reproductive and respiratory syndrome virus

K Zhao, JC Gao, JY Xiong, JC Guo, YB Yang… - Journal of …, 2018 - Am Soc Microbiol
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV)
possesses greater replicative capacity and pathogenicity than classical PRRSV. However …

Cellular miR-130b inhibits replication of porcine reproductive and respiratory syndrome virus in vitro and in vivo

L Li, F Gao, Y Jiang, L Yu, Y Zhou, H Zheng, W Tong… - Scientific reports, 2015 - nature.com
MicroRNAs (miRNAs) can impact viral infections by binding to sequences with partial
complementarity on viral RNA transcripts, usually resulting in the repression of virus …

A conserved stem-loop structure within ORF5 is a frequent recombination hotspot for porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) with a …

M Mötz, J Stadler, H Kreutzmann, A Ladinig, B Lamp… - Viruses, 2023 - mdpi.com
The emergence of recombinant PRRSV strains has been observed for more than a decade.
These recombinant viruses are characterized by a genome that contains genetic material …

[HTML][HTML] Characterization of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1-7-4 viruses) in northern China

C Xie, Z Ha, F Nan, Y Zhang, H Zhang, J Li… - Microbial …, 2020 - Elsevier
The porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of
porcine reproductive and respiratory syndrome (PRRS). Disease outbreaks caused by …

SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci

P Goswami, M Bartas, M Lexa… - Briefings in …, 2021 - academic.oup.com
SARS-CoV-2 is an intensively investigated virus from the order Nidovirales (Coronaviridae
family) that causes COVID-19 disease in humans. Through enormous scientific effort …

Porcine reproductive and respiratory syndrome virus expressing E2 of classical swine fever virus protects pigs from a lethal challenge of highly-pathogenic PRRSV …

F Gao, Y Jiang, G Li, Y Zhou, L Yu, L Li, W Tong… - Vaccine, 2018 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) and classical swine fever (CSF) are
economically significant diseases that affect the swine industry worldwide. However, the …