Recent developments in bioprocessing of recombinant proteins: expression hosts and process development

NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

3D-printed stationary phases with ordered morphology: state of the art and future development in liquid chromatography

C Salmean, S Dimartino - Chromatographia, 2019 - Springer
Stationary phases with precisely ordered morphology have the potential to drastically
improve the performance of chromatographic operations, both in the analytical and in the …

Membrane chromatography and fractionation of proteins from whey—A review

A Nath, MM Zin, MA Molnár, S Bánvölgyi, I Gáspár… - Processes, 2022 - mdpi.com
Membrane chromatography (MC) is an emerging bioseparation technology combining the
principles of membrane filtration and chromatography. In this process, one type of molecule …

Towards next generation high throughput ion exchange membranes for downstream bioprocessing: A review

X Yang, A Merenda, ALA Riyadh, LF Dumée… - Journal of Membrane …, 2022 - Elsevier
Membrane chromatography is recognised as a potential solution to streamline downstream
processing for protein purification, where ion exchange membrane chromatography (IEMC) …

[HTML][HTML] Purification of a monoclonal antibody using a novel high-capacity multimodal cation exchange nonwoven membrane

J Fan, SA Sripada, DN Pham, MY Linova… - Separation and …, 2023 - Elsevier
A high-capacity, multimodal cation exchange (MMC) chromatographic membrane was
developed by conjugating a multimodal ligand–2-mercaptopyridine-3-carboxylic acid …

Comparative evaluation of commercial protein A membranes for the rapid purification of antibodies

J Osuofa, SM Husson - Membranes, 2023 - mdpi.com
Protein A chromatography is ubiquitous to antibody purification. The high specificity of
Protein A for binding the Fc-region of antibodies and related products enables unmatched …

Evolving Paradigms of Recombinant Protein Production in Pharmaceutical Industry: A Rigorous Review

A Jayakrishnan, WR Wan Rosli, ARM Tahir, FSA Razak… - Sci, 2024 - mdpi.com
Many beneficial proteins have limited natural availability, which often restricts their supply
and thereby reduces their potential for therapeutic or industrial usage. The advent of …

Monoclonal antibody capture and analysis using porous membranes containing immobilized peptide mimotopes

W Liu, AL Bennett, W Ning, HY Tan… - Analytical …, 2018 - ACS Publications
Rapid, convenient methods for monoclonal antibody (mAb) isolation are critical for
determining the concentrations of therapeutic mAbs in human serum. This work uses porous …

A review on chromatographic membranes for antibody purification: Factors affecting binding capacity and guidelines for membrane design

Z Dabaghian, E Pakkaner, L Kong, X Yang - Separation and Purification …, 2024 - Elsevier
The rapid increase in antibody demand is urgently calling for high throughput technologies
to enhance the efficiency in downstream purification. Membrane chromatography using …

Matrices and affinity ligands for antibody purification and corresponding applications in radiotherapy

A Xue, S Fan - Biomolecules, 2022 - mdpi.com
Antibodies have become an important class of biological products in cancer treatments such
as radiotherapy. The growing therapeutic applications have driven a demand for high-purity …