The 'ForensOMICS'approach for postmortem interval estimation from human bone by integrating metabolomics, lipidomics, and proteomics

A Bonicelli, HL Mickleburgh, A Chighine, E Locci… - Elife, 2022 - elifesciences.org
The combined use of multiple omics allows to study complex interrelated biological
processes in their entirety. We applied a combination of metabolomics, lipidomics and …

Insights into the differential preservation of bone proteomes in inhumed and entombed cadavers from Italian forensic caseworks

A Bonicelli, A Di Nunzio, C Di Nunzio… - Journal of Proteome …, 2022 - ACS Publications
Bone is a hard biological tissue and a precious reservoir of information in forensic
investigations as it retains key biomolecules commonly used for identification purposes …

Metabolomics in archaeological science: A review of their advances and present requirements

D Badillo-Sanchez, M Serrano Ruber… - Science …, 2023 - science.org
Metabolomics, the study of metabolites (small molecules of< 1500 daltons), has been
posited as a potential tool to explore the past in a comparable manner to other omics, eg …

Proteomic Signatures: A review on forensic bone proteomics and estimation of post-mortem interval

S Arora, J Dalal, K Kumari, S Shukla - Microchemical Journal, 2024 - Elsevier
The determination of the post-mortem interval (PMI) and post-mortem submersion interval
(PMSI) is essential for criminal investigations. It makes use of important data like the cause …

Marine sponge bioerosion in the forensic taphonomy of terrestrial bone

EE Guareschi, CHL Schönberg, PA Magni… - Quaternary …, 2023 - Elsevier
Bone and teeth, specialised bio-mineralized connective tissues, are left after the typical
decomposition process of any vertebrate organism. Their analysis can reveal insights into …

Mitigation of the diagenesis risk in biological apatite δ18O interpretation

C Lécuyer, JP Flandrois - Palaeogeography, Palaeoclimatology …, 2023 - Elsevier
The assessment of the potential blurring effect of diagenetic processes represents the
greatest challenge for geochemists whose purpose is to reconstruct environmental …

[HTML][HTML] Assessing the extent of bone bioerosion in short timescales–a novel approach for quantifying microstructural loss

C Mein, A Williams - Quaternary International, 2023 - Elsevier
The evaluation of bone diagenetic phenomena in archaeological timescales is well
established, but little is known about the extent of bone diagenesis in short forensic …

Examination of human osteoarchaeological remains as a feasible source of polar and apolar metabolites to study past conditions

D Badillo-Sanchez, MS Ruber, AM Davies-Barrett… - Scientific Reports, 2023 - nature.com
Metabolomics is a modern tool that aids in our understanding of the molecular changes in
organisms. Archaeological science is a branch of archaeology that explores different …

Human brains preserve in diverse environments for at least 12 000 years

AL Morton-Hayward, RP Anderson… - … of the Royal …, 2024 - royalsocietypublishing.org
The brain is thought to be among the first human organs to decompose after death. The
discovery of brains preserved in the archaeological record is therefore regarded as unusual …

Effects of pre‐treatment, historical age, and sample characteristics on the stable isotope analyses of killer whale (Orcinus orca) bone

KR Bowen, CM Kurle - Rapid Communications in Mass …, 2024 - Wiley Online Library
Rationale Stable isotope analysis of bone provides insight into animal foraging and allows
for ecological reconstructions over time, however pre‐treatment is required to isolate …