[HTML][HTML] Fracture risk assessment in patients with diabetes mellitus

C Poiana, C Capatina - Journal of Clinical Densitometry, 2017 - Elsevier
Diabetes mellitus, both type 1 and type 2 (T2DM), is associated with decreased bone
strength as well as increased fracture risk. Bone mineral density is decreased in type 1 …

Fracture risk in type 2 diabetes: current perspectives and gender differences

GT Russo, A Giandalia, EL Romeo… - International Journal …, 2016 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic
fractures, resulting in disabilities and increased mortality. The pathophysiological …

Compromised bone healing in aged rats is associated with impaired M2 macrophage function

J Löffler, FA Sass, S Filter, A Rose… - Frontiers in …, 2019 - frontiersin.org
Fracture repair is initiated by a multitude of immune cells and induction of an inflammatory
cascade. Alterations in the early healing response due to an aged adaptive immune system …

A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration

J Löffler, A Noom, A Ellinghaus, A Dienelt… - Communications …, 2023 - nature.com
Bone regeneration after fracture is a complex process with high and dynamic energy
demands. The impact of metabolism on bone healing progression and outcome, however, is …

Assessment risk of osteoporosis in Chinese people: relationship among body mass index, serum lipid profiles, blood glucose, and bone mineral density

R Cui, L Zhou, Z Li, Q Li, Z Qi… - Clinical interventions in …, 2016 - Taylor & Francis
Objective The aim of our study was to investigate the relationship among age, sex, body
mass index (BMI), serum lipid profiles, blood glucose (BG), and bone mineral density (BMD) …

Imaging techniques to study diabetic bone disease

J Carballido-Gamio - Current Opinion in Endocrinology, Diabetes …, 2022 - journals.lww.com
As bone fragility in diabetes is not explained by DXA-derived aBMD and given the limitations
of cross-sectional studies, it is imperative to use 3D imaging techniques for longitudinal …

Bone–fat interaction

E Rendina-Ruedy, CJ Rosen - Endocrinology and Metabolism …, 2017 - endo.theclinics.com
Osteoporosis and low bone mass (ie, osteopenia) are major public health concerns affecting
a staggering 54 million in the United States. 1 Moreover, as the nation's demographic …

Increased fracture risk in patients with type 2 diabetes mellitus: an overview of the underlying mechanisms and the usefulness of imaging modalities and fracture risk …

EAC De Waard, TACM van Geel, HHCM Savelberg… - Maturitas, 2014 - Elsevier
Type 2 diabetes mellitus has recently been linked to an increased fracture risk. Since bone
mass seems to be normal to elevated in patient with type 2 diabetes, the increased fracture …

CD31+ cells from peripheral blood facilitate bone regeneration in biologically impaired conditions through combined effects on immunomodulation and angiogenesis

FA Sass, K Schmidt‐Bleek, A Ellinghaus… - Journal of Bone and …, 2017 - academic.oup.com
Controlled revascularization and inflammation are key elements regulating endogenous
regeneration after (bone) tissue trauma. Peripheral blood‐derived cell subsets, such as …

Do patients with type 2 diabetes have impaired hip bone microstructure? A study using 3D modeling of hip dual-energy X-ray absorptiometry

E Ubago-Guisado, E Moratalla-Aranda… - Frontiers in …, 2023 - frontiersin.org
Aim Patients with type 2 diabetes (T2DM) have more risk of bone fractures. However, areal
bone mineral density (aBMD) by conventional dual-energy x-ray absorptiometry (DXA) is not …