[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Advancing glaucoma care: integrating artificial intelligence in diagnosis, management, and progression detection

Y Zhu, R Salowe, C Chow, S Li, O Bastani, JM O'Brien - Bioengineering, 2024 - mdpi.com
Glaucoma, the leading cause of irreversible blindness worldwide, comprises a group of
progressive optic neuropathies requiring early detection and lifelong treatment to preserve …

Impact of smoking on visual field progression in a long-term clinical follow-up

G Mahmoudinezhad, T Nishida, RN Weinreb… - Ophthalmology, 2022 - Elsevier
Purpose To investigate the effect of smoking on rates of progressive visual field (VF)
damage over time in glaucoma. Design Retrospective cohort study. Participants Five …

Smoking and progressive retinal nerve fibre layer thinning in glaucoma

T Nishida, G Mahmoudinezhad, RN Weinreb… - British Journal of …, 2023 - bjo.bmj.com
Background/Aims To investigate the relationship between smoking and smoking intensity,
and the rate of retinal nerve fibre layer (RNFL) thinning in patients with primary open angle …

Association between rate of ganglion cell complex thinning and rate of central visual field loss

G Mahmoudinezhad, S Moghimi, T Nishida… - JAMA …, 2023 - jamanetwork.com
Importance Whether rapid ganglion cell complex (GCC) thinning during an initial follow-up
period is associated with rates of central visual field loss over time is unclear but important to …

Impact of social vulnerability index on the development of severe visual impairment or blindness from glaucoma

SS Swaminathan, FA Medeiros, SJ Gedde - American journal of …, 2024 - Elsevier
Purpose To evaluate whether geocoded social risk factor data predict the development of
severe visual impairment or blindness due to glaucoma during follow-up using a large …

Association of initial optical coherence tomography angiography vessel density loss with faster visual field loss in glaucoma

T Nishida, S Moghimi, JH Wu, AC Chang… - JAMA …, 2022 - jamanetwork.com
Importance Rapid vessel density loss during an initial follow-up period may be associated
with the rates of visual field loss over time. Objectives To evaluate the association between …

Rate of Initial Optic Nerve Head Capillary Density Loss and Risk of Visual Field Progression

N Tansuebchueasai, T Nishida, S Moghimi… - JAMA …, 2024 - jamanetwork.com
Importance Rapid initial optic nerve head capillary density loss may be used to assess the
risk of glaucoma visual field progression. Objective To investigate the association between …

Application of diffusion tensor imaging technology in glaucoma diagnosis

J Wang, Y Zhang, X Meng, G Liu - Frontiers in neuroscience, 2023 - frontiersin.org
Glaucoma is the first major category of irreversible blinding eye illnesses worldwide. Its
leading cause is the death of retinal ganglion cells and their axons, which results in the loss …

Risk factors for structural and functional progression of primary open-angle glaucoma in an African ancestry cohort

RJ Salowe, Y Chen, S Zenebe-Gete… - BMJ Open …, 2023 - bmjophth.bmj.com
Background/aims To investigate the rates of structural and functional progression of primary
open-angle glaucoma in an African ancestry cohort and identify risk factors for progression …