Biocatalytic reduction reactions from a chemist's perspective

F Hollmann, DJ Opperman… - Angewandte Chemie …, 2021 - Wiley Online Library
Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Engineering Fatty Acid Photodecarboxylase to Enable Highly Selective Decarboxylation of trans Fatty Acids

D Li, T Han, J Xue, W Xu, J Xu, Q Wu - Angewandte Chemie, 2021 - Wiley Online Library
Due to the high risk of heart disease caused by the intake of trans fatty acids, a method to
eliminate trans fatty acids from foods has become a critical issue. Herein, we engineered …

Production of biobased ethylbenzene by cascade biocatalysis with an engineered photodecarboxylase

Z Qin, Y Zhou, Z Li, M Höhne… - Angewandte Chemie …, 2024 - Wiley Online Library
Production of commodity chemicals, such as benzene, toluene, ethylbenzene, and xylenes
(BTEX), from renewable resources is key for a sustainable society. Biocatalysis enables one …

Intensification of photobiocatalytic decarboxylation of fatty acids for the production of biodiesel

HT Duong, Y Wu, A Sutor, BO Burek… - …, 2021 - Wiley Online Library
Light‐driven biocatalytic processes are notoriously hampered by poor penetration of light
into the turbid reaction media. In this study, wirelessly powered light‐emitting diodes are …

Stabilisation of the Fatty Acid Decarboxylase from Chlorella variabilis by Caprylic Acid

Y Wu, CE Paul, F Hollmann - ChemBioChem, 2021 - Wiley Online Library
The fatty acid photodecarboxylase from Chlorella variabilis NC64 A (CvFAP) catalyses the
light‐dependent decarboxylation of fatty acids. Photoinactivation of CvFAP still represents …

Photobiocatalytic decarboxylation for the synthesis of fatty epoxides from renewable fatty acids

R Ge, P Zhang, X Dong, Y Li, Z Sun, Y Zeng… - …, 2022 - Wiley Online Library
Fatty epoxides are unique building blocks in organic transformations and materials
production; however, their synthetic methodologies are currently not accessible from …

Immobilization and application of fatty acid photodecarboxylase in deep eutectic solvents

SN Chanquia, FV Benfeldt, N Petrovai… - …, 2022 - Wiley Online Library
Since its discovery in 2017, the fatty acid decarboxylase (FAP) photoenzyme has been the
focus of extensive research, given its ability to convert fatty acids into alka (e) nes using …

Carboxylic acid reductase can catalyze ester synthesis in aqueous environments

P Pongpamorn, C Kiattisewee… - Angewandte …, 2021 - Wiley Online Library
Most of the well‐known enzymes catalyzing esterification require the minimization of water
or activated substrates for activity. This work reports a new reaction catalyzed by carboxylic …

Rational Engineering of a Multi‐Step Biocatalytic Cascade for the Conversion of Cyclohexane to Polycaprolactone Monomers in Pseudomonas taiwanensis

L Schäfer, K Bühler, R Karande… - Biotechnology …, 2020 - Wiley Online Library
The current industrial production of polymer building blocks such as ε‐caprolactone (ε‐CL)
and 6‐hydroxyhexanoic acid (6HA) is a multi‐step process associated with critical …

Biokatalytische Reduktionen aus der Sicht eines Chemikers

F Hollmann, DJ Opperman, CE Paul - Angewandte Chemie, 2021 - Wiley Online Library
Reduktionsreaktionen spielen eine zentrale Rolle in der organischen Chemie zur Synthese
chiraler Produkte. Insbesondere Enzyme katalysieren solche Reaktionen in hoher Stereo …