Current status and applications of somatic cell nuclear transfer in dogs

G Jang, MK Kim, BC Lee - Theriogenology, 2010 - Elsevier
Although somatic cell nuclear transfer (SCNT) technology and applications are well
developed in most domesticated and laboratory animals, their use in dogs has advanced …

Health and temperaments of cloned working dogs

MJ Kim, HJ Oh, SY Hwang, TY Hur… - Journal of Veterinary …, 2018 - synapse.koreamed.org
Dogs serve human society in various ways by working at tasks that are based on their
superior olfactory sensitivity. However, it has been reported that only about half of all trained …

Recloned dogs derived from adipose stem cells of a transgenic cloned beagle

HJ Oh, JE Park, MJ Kim, SG Hong, JC Ra, JY Jo… - Theriogenology, 2011 - Elsevier
A number of studies have postulated that efficiency in mammalian cloning is inversely
correlated with donor cell differentiation status and may be increased by using …

Influence of oocyte donor and embryo recipient conditions on cloning efficiency in dogs

MJ Kim, HJ Oh, JE Park, SG Hong, JT Kang, OJ Koo… - Theriogenology, 2010 - Elsevier
To determine factors that affect the efficiency of dog cloning by somatic cell nuclear transfer,
the present study was performed to investigate 1) the effects of surgical history (non …

Dog cloning—no longer science fiction

SH Lee, HJ Oh, MJ Kim, GA Kim… - … in Domestic Animals, 2018 - Wiley Online Library
Contents Since the generation of world's first cloned dog, Snuppy, in 2005, somatic cell
nuclear transfer (SCNT) in dogs has been widely applied for producing several kinds of …

Behavioral analysis of cloned puppies derived from an elite drug-detection dog

J Choi, JH Lee, HJ Oh, MJ Kim, GA Kim, EJ Park… - Behavior genetics, 2014 - Springer
Since the first cloned dog “Snuppy” was born, many cloned dogs have been produced by
somatic cell nuclear transfer (SCNT) technology. We reported the production of seven …

Effective donor cell fusion conditions for production of cloned dogs by somatic cell nuclear transfer

JE Park, HJ Oh, SG Hong, MJ Kim, GA Kim, OJ Koo… - Theriogenology, 2011 - Elsevier
As shown by the birth of the first cloned dog 'Snuppy', a protocol to produce viable cloned
dogs has been reported. In order to evaluate optimum fusion conditions for improving dog …

Donor-matched functional and molecular characterization of canine mesenchymal stem cells derived from different origins

SA Ock, GH Maeng, YM Lee, TH Kim… - Cell …, 2013 - journals.sagepub.com
Canine mesenchymal stem cells (cMSCs) have generated a great interest as a promising
source for cell-based therapies. To understand the basic biological properties of cMSCs …

Induced pluripotent stem cells—a new foundation in medicine

GTJ Huang - Journal of Experimental & Clinical Medicine, 2010 - Elsevier
Generation of induced pluripotent stem (iPS) cells using defined factors has been
considered a ground-breaking step towards establishing patient-specific pluripotent stem …

Propagation of elite rescue dogs by somatic cell nuclear transfer

HJ Oh, J Choi, MJ Kim, GA Kim, YK Jo… - Animal Science …, 2016 - Wiley Online Library
The objective of the present study was to compare the efficiency of two oocyte activation
culture media to produce cloned dogs from an elite rescue dog and to analyze their …