Benzofuran compounds are a class of compounds that are ubiquitous in nature. Numerous
studies have shown that most benzofuran compounds have strong biological activities such …

Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders with
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …

Alzheimer's disease (AD) is a multifactorial syndrome resulting in profound misery and
poses a substantial burden on human health, economy, and society throughout the world …

To obtain a multipotent framework that can target simultaneously COX-2, 5-LOX,
acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) to treat neuroinflammation …

The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …

Alzheimer's disease (AD) is a genetically complex, progressive and irreversible
neurodegenerative disorder of the brain which involves multiple associated etiological …

The enzymatic activity of butyrylcholinesterase (BChE) in the brain increases with the
progression of Alzheimer's disease, thus classifying BChE as a promising drug target in …

The amyloid cascade hypothesis has been dominating drug discovery for Alzheimer's
disease (AD) for the last two decades. The failure of the development of effective drugs for …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no clinically
accepted treatment to cure or halt its progression. The Food and Drug Administration has …