The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications

B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactions

LMD Magalhães, KJ Gollob, B Zingales… - The Lancet …, 2022 - thelancet.com
The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa

M Tibayrenc, FJ Ayala - Proceedings of the National …, 2012 - National Acad Sciences
We propose that clonal evolution in micropathogens be defined as restrained recombination
on an evolutionary scale, with genetic exchange scarce enough to not break the prevalent …

The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets

F Altamura, R Rajesh, CMC Catta‐Preta… - Drug development …, 2022 - Wiley Online Library
Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

Chagas disease diagnostic applications: present knowledge and future steps

V Balouz, F Agüero, CA Buscaglia - Advances in parasitology, 2017 - Elsevier
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Shotgun Sequencing Analysis of Trypanosoma cruzi I Sylvio X10/1 and Comparison with T. cruzi VI CL Brener

O Franzen, S Ochaya, E Sherwood… - PLoS neglected …, 2011 - journals.plos.org
Trypanosoma cruzi is the causative agent of Chagas disease, which affects more than 9
million people in Latin America. We have generated a draft genome sequence of the TcI …

Evolutionary insights from bat trypanosomes: morphological, developmental and phylogenetic evidence of a new species, Trypanosoma (Schizotrypanum) erneyi sp …

L Lima, FM Da Silva, L Neves, M Attias, CSA Takata… - Protist, 2012 - Elsevier
Parasites of the genus Trypanosoma are common in bats and those of the subgenus
Schizotrypanum are restricted to bats throughout the world, with the exception of …

The compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: an increasingly complex puzzle

G Mitta, B Gourbal, C Grunau, M Knight… - Advances in …, 2017 - Elsevier
This review reexamines the results obtained in recent decades regarding the compatibility
polymorphism between the snail, Biomphalaria glabrata, and the pathogen, Schistosoma …

How clonal are Trypanosoma and Leishmania?

M Tibayrenc, FJ Ayala - Trends in parasitology, 2013 - cell.com
The clonal theory of parasitic protozoa has been recently challenged by researchers stating
that recombination in Kinetoplastida is much more frequent than previously believed, or that …

Basic biology of Trypanosoma cruzi

AA Zuma, E dos Santos Barrias… - Current pharmaceutical …, 2021 - ingentaconnect.com
The present review addresses basic aspects of the biology of the pathogenic protozoa
Trypanosoma cruzi and some comparative information of Trypanosoma brucei. Like …