COVID-19 vaccination: The road ahead

DM Altmann, RJ Boyton - Science, 2022 - science.org
A diverse array of successful, first-generation SARS-CoV-2 vaccines have played a huge
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …

Overview of the main anti-SARS-CoV-2 vaccines: mechanism of action, efficacy and safety

MT Mascellino, F Di Timoteo… - Infection and drug …, 2021 - Taylor & Francis
This review takes into consideration the principal vaccines developed against the SARS-
CoV-2 in this unprecedented period of Covid-19 pandemic. We evaluated the mechanism of …

Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure

CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin… - Science, 2022 - science.org
The Omicron, or Pango lineage B. 1.1. 529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

[HTML][HTML] Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million …

U Agrawal, S Bedston, C McCowan, J Oke, L Patterson… - The Lancet, 2022 - thelancet.com
Background Current UK vaccination policy is to offer future COVID-19 booster doses to
individuals at high risk of serious illness from COVID-19, but it is still uncertain which groups …

[HTML][HTML] Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study

C Menni, K Klaser, A May, L Polidori… - The Lancet Infectious …, 2021 - thelancet.com
Summary Background The Pfizer-BioNTech (BNT162b2) and the Oxford-AstraZeneca
(ChAdOx1 nCoV-19) COVID-19 vaccines have shown excellent safety and efficacy in phase …

Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2

JE Ebinger, J Fert-Bober, I Printsev, M Wu, N Sun… - Nature medicine, 2021 - nature.com
In a cohort of BNT162b2 (Pfizer–BioNTech) mRNA vaccine recipients (n= 1,090), we
observed that spike-specific IgG antibody levels and ACE2 antibody binding inhibition …

Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

RP Payne, S Longet, JA Austin, DT Skelly… - Cell, 2021 - cell.com
Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was
introduced in the United Kingdom to accelerate population coverage with a single dose. At …

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

CJ Reynolds, C Pade, JM Gibbons, DK Butler, AD Otter… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine rollout has
coincided with the spread of variants of concern. We investigated whether single-dose …

[HTML][HTML] Reduced risk of reinfection with SARS-CoV-2 after COVID-19 vaccination—Kentucky, May–June 2021

AM Cavanaugh - MMWR. Morbidity and mortality weekly report, 2021 - cdc.gov
Discussion This study found that among Kentucky residents who were previously infected
with SARS-CoV-2 in 2020, those who were unvaccinated against COVID-19 had …

[HTML][HTML] COVID-19 vaccine challenges: What have we learned so far and what remains to be done?

R Forman, S Shah, P Jeurissen, M Jit, E Mossialos - Health policy, 2021 - Elsevier
Abstracts Developing and distributing a safe and effective SARS-CoV-2 (COVID-19) vaccine
has garnered immense global interest. Less than a year after COVID-19 was declared a …