Early life adversity (ELA)-which includes physical, psychological, emotional, and sexual
abuse is one of the most common predictors to diverse psychopathologies later in …

Epigenomic modifications of the brain-derived neurotrophic factor (BDNF) gene have been
postulated to underlie the pathogenesis of neurodevelopmental, psychiatric, and …

The pervasiveness and mortality associated with methamphetamine abuse have doubled
during the past decade, suggesting a possible worldwide substance use crisis. Epitomizing …

Brain-derived neurotrophic factor (BDNF) is a major neurotrophin whose loss or interruption
is well established to have numerous intersections with the pathogenesis of progressive …

Methamphetamine (METH) is an illicit psychostimulant that is widely abused. The molecular
mechanism of METH addiction is complicated and still unknown. METH causes the release …

Synaptic plasticity is the capacity of synaptic transmission between neurons to be
strengthened or weakened. There are many signal molecules accumulated in the …

Addiction is a chronically relapsing neuropsychiatric disease that occurs in some, but not all,
individuals who use substances of abuse. Relatively little is known about the mechanisms …

Substance use disorders (SUDs) are complex biopsychosocial diseases that cause
neurocognitive deficits and neurological impairments by altering the gene expression in …

Aim: To identify the DNA methylation status of related genes in major depressive disorder
following selective serotonin-reuptake inhibitor treatment. Materials & methods: 45 patients …

DNA methylation is an important epigenetic modification that regulates many biological
processes. The sea cucumber Apostichopus japonicus often suffers from heat stress that …