Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …

Molecular point-of-care (POC) tests offer high sensitivity, rapid turnaround times, relative
ease of use, and the convenience of laboratory-grade testing in the absence of formal …

Infections caused by bacteria have a major impact on public health-related morbidity and
mortality. Despite major advances in the prevention and treatment of bacterial infections, the …

Invasive fungal infections continue to increase as at-risk populations expand. The high
associated morbidity and mortality with fungal diseases mandate the continued investigation …

Background Cryptococcal meningitis is a common cause of AIDS-related mortality. Although
symptom recurrence after initial treatment is common, the etiology is often difficult to …

Background The incidence of cryptococcosis amongst HIV-negative persons is increasing.
Whilst the excellent performance of the CrAg testing in people living with HIV is well …

Introduction Central nervous system infections (CNSI) disproportionately affect individuals in
low-resource settings where diagnosis is challenging; large proportions of patients never …

Background: Seroprevalence studies have shown that 70% of children are exposed to
Cryptococcus, the most common cause of meningitis in people living with human …

Cryptococcal meningitis is an important global health problem, resulting from infection with
the yeast Cryptococcus, especially Cryptococcus neoformans and Cryptococcus gattii, which …