Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
mammalian brain, essential not only to the development of the central nervous system but …

Background The non-prescription medication paracetamol (acetaminophen, APAP) is
currently recommended as a safe pain and fever treatment during pregnancy. However …

Background In light of the vulnerability of the developing brain, mixture risk assessment
(MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented …

Omega-3 long chain polyunsaturated fatty acid supplementation (n-3 LCPUFA) for treatment
of Autism Spectrum Disorder (ASD) is popular. The results of previous systematic reviews …

There is now compelling evidence that gene by environment interactions are important in
the etiology of autism spectrum disorders (ASDs). However, the mechanisms by which …

Brain-derived neurotrophic factor (BDNF) plays an important role in activity-dependent
synaptic plasticity. Altered blood BDNF levels have been frequently identified in people with …

The gut–brain axis refers to the bidirectional communication between the enteric nervous
system and the central nervous system. Mounting evidence supports the premise that the …

Importance Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF)
may be implicated in the developmental outcomes of children with autism spectrum disorder …

Accumulating evidence suggests that the origins of adult disease may occur during fetal life.
Thus, the concept of “developmental programming” has been introduced and supported by …

Omega-3 polyunsaturated fatty acids (or omega-3 PUFAs, n-3 PUFAs) are essential
nutrients throughout the life span. Recent studies have shown the importance of n-3 PUFAs …