[HTML][HTML] Evidence for the benefits of melatonin in cardiovascular disease
The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …
[HTML][HTML] Erectile dysfunction: pharmacological pathways with understudied potentials
Erectile dysfunction (ED) is a public health concern worldwide. In the past, it was perceived
as a phenomenon attributed to age advancement. However, more individuals are affected …
as a phenomenon attributed to age advancement. However, more individuals are affected …
[HTML][HTML] Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation
L Yu, W Di, X Dong, Z Li, Y Zhang, X Xue, Y Xu… - … et Biophysica Acta (BBA …, 2018 - Elsevier
It has been demonstrated that the anti-oxidative and cardioprotective effects of melatonin
are, at least in part, mediated by its membrane receptors. However, the direct downstream …
are, at least in part, mediated by its membrane receptors. However, the direct downstream …
[HTML][HTML] Melatonin, a natural antioxidant therapy in spinal cord injury
L Xie, H Wu, X Huang, T Yu - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a sudden onset of disruption to the spinal neural tissue, leading to
loss of motor control and sensory function of the body. Oxidative stress is considered a …
loss of motor control and sensory function of the body. Oxidative stress is considered a …
Biomaterial strategies for limiting the impact of secondary events following spinal cord injury
TR Ham, ND Leipzig - Biomedical Materials, 2018 - iopscience.iop.org
The nature of traumatic spinal cord injury (SCI) often involves limited recovery and long-term
quality of life complications. The initial injury sets off a variety of secondary cascades, which …
quality of life complications. The initial injury sets off a variety of secondary cascades, which …
[HTML][HTML] Proniosomal Gel-Loaded Phosphodiesterase Inhibitors (Sildenafil, Vardenafil, and Tadalafil): Prospects for Topical Penile Therapy of Tadalafil for Treatment …
Oral phosphodiesterase inhibitors have emerged as a game changer for the treatment of
erectile dysfunction (ED) since attaining FDA approval for its first member, sildenafil, in 1998 …
erectile dysfunction (ED) since attaining FDA approval for its first member, sildenafil, in 1998 …
[HTML][HTML] Asiaticoside attenuates the effects of spinal cord injury through antioxidant and anti‑inflammatory effects, and inhibition of the p38‑MAPK mechanism
Y Luo, C Fu, Z Wang, Z Zhang… - Molecular Medicine …, 2015 - spandidos-publications.com
Asiaticoside has potent pharmacological activity and broader pharmacological effects,
including anti‑oxidant, antidepressant and hepatic protection effects, and the inhibition of …
including anti‑oxidant, antidepressant and hepatic protection effects, and the inhibition of …
[HTML][HTML] Melatonin for the treatment of spinal cord injury
Y Zhang, WX Zhang, YJ Zhang, YD Liu… - Neural regeneration …, 2018 - journals.lww.com
Spinal cord injury (SCI) from trauma or disease severely impairs sensory and motor function.
Neurorehabilitation after SCI is a complex medical process that focuses on improving …
Neurorehabilitation after SCI is a complex medical process that focuses on improving …
Resveratrol treatment may preserve the erectile function after radiotherapy by restoring antioxidant defence mechanisms, SIRT1 and NOS protein expressions
Radiotherapy (RT) for prostate cancer (PC) can cause erectile dysfunction (ED) by
damaging neurovascular structures with oxidative stress. In this study, we evaluated the …
damaging neurovascular structures with oxidative stress. In this study, we evaluated the …
Melatonin for spinal cord injury in animal models: a systematic review and network meta-analysis
L Yang, M Yao, Y Lan, W Mo, Y Sun, J Wang… - Journal of …, 2016 - liebertpub.com
Spinal cord injury (SCI) leads to loss of function below the lesion and affects individuals
worldwide. An increasing number of experimental studies support the effectiveness of …
worldwide. An increasing number of experimental studies support the effectiveness of …