Hirschsprung disease (HSCR) is a rare congenital intestinal disease that occurs in 1 in
5,000 live births. HSCR is characterized by the absence of ganglion cells in the myenteric …

Background Hirschsprung's disease (HSCR) is a serious congenital bowel disorder with a
prevalence of 1/5000. Currently, there is a lack of systematically developed guidelines to …

Progress in our understanding of the pathophysiology, prevention and treatment of
necrotizing enterocolitis (NEC) has been hampered for many reasons. Included among …

The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

Diagnosis or exclusion of Hirschsprung disease (HSCR) is a frequent exercise in any
pediatric hospital. Although HSCR may present at different ages and with varied clinical …

Hirschsprung-associated enterocolitis (HAEC) was described in 1886 by Harald
Hirschsprung and is a potentially deadly complication of Hirschsprung Disease. HAEC is …

Hirschsprung's disease (HSCR) is a congenital disorder characterized by failure of the
neural crest cells to migrate and populate the distal bowel during gestation affecting different …

Purpose Hirschsprung's associated enterocolitis (HAEC) is a complication of Hirschsprung's
Disease (HD) with considerable morbidity and mortality. The variability in presentation leads …

Children with Hirschsprung disease have postoperative long-term sequelae in defecation
that contribute to morbidity and mortality and significantly impact their quality of life. Pediatric …

Endorectal pullthrough surgery is integral in the treatment of patients with Hirschsprung
disease. Several different surgical procedures exist, which share as common goals to excise …