Cognitive decline is a broad syndrome ranging from non-pathological/age-associated
cognitive decline to pathological dementia. Mild cognitive impairment MCI) is defined as the …

Objective To compare acute treatment responses and long-term outcome in leucine-rich
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …

Clinical trials with anti-tau drugs will need to target individuals at risk of accumulating tau.
Our objective was to identify variables available in a research setting that predict future rates …

Altered iron metabolism has been hypothesized to be associated with Alzheimer's disease
pathology, and prior work has shown associations between iron load and beta amyloid …

We report a group of patients presenting with a progressive dementia syndrome
characterized by predominant dysfunction in core executive functions, relatively young age …

Background Colony‐stimulating factor‐1 receptor (CSF1R)‐related leukoencephalopathy is
a rapidly progressive neurodegenerative disease for which there is currently no cure …

Background and Objectives Corticobasal syndrome (CBS) is a clinical phenotype
characterized by asymmetric parkinsonism, rigidity, myoclonus, and apraxia. Originally …

Background: A key challenge in studies that model outcomes, disease progression, and cost-
effectiveness of existing and emerging dementia treatments is the lack of conversion criteria …

There is no health without brain health, which is threatened by rising curves of stroke,
ischemic heart disease, and dementia (the triple threat). The fastest growing and intractable …

Background: There are detectable cognitive differences in cognitively unimpaired (CU)
individuals with preclinical Alzheimer's disease (AD). Objective: To determine whether cross …