Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies
YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
[HTML][HTML] COVID-19: systemic pathology and its implications for therapy
Q Shen, J Li, Z Zhang, S Guo, Q Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Responding to the coronavirus disease 2019 (COVID-19) pandemic has been an
unexpected and unprecedented global challenge for humanity in this century. During this …
unexpected and unprecedented global challenge for humanity in this century. During this …
Lactobacillus rhamnosus Restores Antiviral Signaling and Attenuates Cytokines Secretion from Human Bronchial Epithelial Cells Exposed to Cigarette Smoke and …
Individuals with chronic obstructive pulmonary disease (COPD) are more susceptible to
exacerbation crisis triggered by secondary lung infections due to the dysfunction of antiviral …
exacerbation crisis triggered by secondary lung infections due to the dysfunction of antiviral …
Bioinformatics analyses reveal cell-barrier junction modulations in lung epithelial cells on SARS-CoV-2 infection
Cell junctions maintain the blood-tissue barriers to preserve vascular and tissue integrity.
Viral infections reportedly modulate cell–cell junctions to facilitate their invasion. However …
Viral infections reportedly modulate cell–cell junctions to facilitate their invasion. However …
A multi-arm, parallel, preclinical study investigating the potential benefits of acetazolamide, candesartan, and triciribine in combination with fluconazole for the …
AH Alanazi, DB Chastain, M Rudraraju… - European Journal of …, 2023 - Elsevier
Cryptococcus neoformans, an opportunistic fungal pathogen, primarily infects
immunodeficient patients frequently causing cryptococcal meningoencephalitis (CM) …
immunodeficient patients frequently causing cryptococcal meningoencephalitis (CM) …
[HTML][HTML] Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy
Proliferative retinopathies are the leading cause of irreversible blindness in all ages, and
there is a critical need to identify novel therapies. We investigated the impact of triciribine …
there is a critical need to identify novel therapies. We investigated the impact of triciribine …