Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic …
A Yim, C Smith, AM Brown - Immunological reviews, 2022 - Wiley Online Library
Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
RNA viruses: ROS‐mediated cell death
ML Reshi, YC Su, JR Hong - International journal of cell …, 2014 - Wiley Online Library
Reactive oxygen species (ROS) are well known for being both beneficial and deleterious.
The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus …
The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus …
Cytokine effects on the basal ganglia and dopamine function: the subcortical source of inflammatory malaise
Data suggest that cytokines released during the inflammatory response target subcortical
structures including the basal ganglia as well as dopamine function to acutely induce …
structures including the basal ganglia as well as dopamine function to acutely induce …
Neuroinflammation in addiction: A review of neuroimaging studies and potential immunotherapies
Addiction is a worldwide public health problem and this article reviews scientific advances in
identifying the role of neuroinflammation in the genesis, maintenance, and treatment of …
identifying the role of neuroinflammation in the genesis, maintenance, and treatment of …
Drug–drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems
Introduction: Substance abuse is a common problem among HIV-infected individuals.
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
Methamphetamine and its immune-modulating effects
The recreational use of methamphetamine (METH, or ice) is a global burden. It pervades
and plagues contemporary society; it has been estimated that there are up to 35 million …
and plagues contemporary society; it has been estimated that there are up to 35 million …
Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in …
A Shah, PS Silverstein, DP Singh, A Kumar - Journal of neuroinflammation, 2012 - Springer
Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous
system toxicity of MA is well documented. The mechanisms contributing to this toxicity have …
system toxicity of MA is well documented. The mechanisms contributing to this toxicity have …
HIV gp120-and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1
Abstract HIV-1 glycoprotein 120 (gp120) is known to cause neurotoxicity via several
mechanisms including production of proinflammatory cytokines/chemokines and oxidative …
mechanisms including production of proinflammatory cytokines/chemokines and oxidative …
Effect of mild-to-moderate smoking on viral load, cytokines, oxidative stress, and cytochrome P450 enzymes in HIV-infected individuals
A Ande, C McArthur, L Ayuk, C Awasom, PN Achu… - PloS one, 2015 - journals.plos.org
Mild-to-moderate tobacco smoking is highly prevalent in HIV-infected individuals, and is
known to exacerbate HIV pathogenesis. The objective of this study was to determine the …
known to exacerbate HIV pathogenesis. The objective of this study was to determine the …
Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes
Introduction: Alcohol consumption, which is highly prevalent in HIV-infected individuals,
poses serious concerns in terms of rate of acquisition of HIV-1 infection, HIV-1 replication …
poses serious concerns in terms of rate of acquisition of HIV-1 infection, HIV-1 replication …