Access to CAR T-cell therapy: Focus on diversity, equity and inclusion
MS Odstrcil, CJ Lee, C Sobieski, D Weisdorf, D Couriel - Blood Reviews, 2024 - Elsevier
Chimeric antigen receptor T-cell (CAR T-cell) therapy has revolutionized the treatment of
hematologic malignancies in patients with relapsed or refractory disease without other …
hematologic malignancies in patients with relapsed or refractory disease without other …
[HTML][HTML] Chimeric antigen receptor T cell therapy for myeloma: where are we now and what is needed to move chimeric antigen receptor T cells forward to earlier lines …
Since 2021, 2 B cell maturation antigen (BCMA)-directed chimeric antigen receptor T cell
(CAR-T) therapies—idecabtagene vicleucel (ide-cel), and ciltacabtagene autoleucel (cilta …
(CAR-T) therapies—idecabtagene vicleucel (ide-cel), and ciltacabtagene autoleucel (cilta …
Spleen SORT LNP generated in situ CAR T cells extend survival in a mouse model of lymphoreplete B cell lymphoma
E Álvarez‐Benedicto, Z Tian, S Chatterjee… - Angewandte …, 2023 - Wiley Online Library
Abstract Chimeric Antigen Receptor (CAR) T cell immunotherapy is revolutionizing treatment
for patients suffering from B‐cell lymphoma (BL). However, the current method of CAR T cell …
for patients suffering from B‐cell lymphoma (BL). However, the current method of CAR T cell …
[HTML][HTML] The paths and challenges of “off-the-shelf” CAR-T cell therapy: An overview of clinical trials
V Moradi, A Omidkhoda, N Ahmadbeigi - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The advent of chimeric antigen receptor T cells (CAR-T cells) has made a tremendous
revolution in the era of cancer immunotherapy, so that since 2017 eight CAR-T cell products …
revolution in the era of cancer immunotherapy, so that since 2017 eight CAR-T cell products …
New cell sources for CAR-based immunotherapy
M Mazinani, F Rahbarizadeh - Biomarker Research, 2023 - Springer
Chimeric antigen receptor (CAR) T cell therapy, in which a patient's own T lymphocytes are
engineered to recognize and kill cancer cells, has achieved striking success in some …
engineered to recognize and kill cancer cells, has achieved striking success in some …
The application of autologous cancer immunotherapies in the age of memory-NK cells
GD Lizana-Vasquez, M Torres-Lugo, RB Dixon… - Frontiers in …, 2023 - frontiersin.org
Cellular immunotherapy has revolutionized the oncology field, yielding improved results
against hematological and solid malignancies. NK cells have become an attractive …
against hematological and solid malignancies. NK cells have become an attractive …
Nanomaterials Boost CAR‐T Therapy for Solid Tumors
J Long, Y Wang, X Jiang, J Ge, M Chen… - Advanced …, 2024 - Wiley Online Library
T cell engineering, particularly via chimeric antigen receptor (CAR) modifications for
enhancing tumor specificity, has shown efficacy in treating hematologic malignancies. The …
enhancing tumor specificity, has shown efficacy in treating hematologic malignancies. The …
Expanding CAR-T cell immunotherapy horizons through microfluidics
Chimeric antigen receptor (CAR)-T cell therapies have revolutionized cancer treatment,
particularly in hematological malignancies. However, their application to solid tumors is …
particularly in hematological malignancies. However, their application to solid tumors is …
Redefining cancer research for therapeutic breakthroughs
AE Yuzhalin - British journal of cancer, 2024 - nature.com
Cancer research has played a pivotal role in improving patient outcomes. However, despite
the significant investment in fundamental cancer research over the past few decades, the …
the significant investment in fundamental cancer research over the past few decades, the …
Revolutionizing cancer treatment: a comprehensive review of CAR-T cell therapy
Chimeric antigen receptor (CAR)-T cell therapy is a promising new treatment for cancer that
involves genetically modifying a patient's T-cells to recognize and attack cancer cells. This …
involves genetically modifying a patient's T-cells to recognize and attack cancer cells. This …