On the road to accurate protein biomarkers in prostate cancer diagnosis and prognosis: current status and future advances

Y Yan, SY Yeon, C Qian, S You, W Yang - International Journal of …, 2021 - mdpi.com
Prostate cancer (PC) is a leading cause of morbidity and mortality among men worldwide.
Molecular biomarkers work in conjunction with existing clinicopathologic tools to help …

Histopathological concordance between prostate biopsies and radical prostatectomy specimens—Implications of transrectal and transperineal biopsy approaches

MJ Hagens, LLA Ribbert, A Jager, H Veerman… - Prostate cancer and …, 2024 - nature.com
Background This study aimed to evaluate the histopathological concordance rates between
prostate biopsies and radical prostatectomy specimens according to the applied biopsy …

Adverse upgrading and/or upstaging in contemporary low-risk prostate cancer patients

RS Flammia, B Hoeh, L Hohenhorst, G Sorce… - … Urology and Nephrology, 2022 - Springer
Background Upgrading and/or upstaging in low-risk prostate cancer (PCa) patients may
represent an indication for active treatment instead of active surveillance (AS). We …

An external validation of the nocera nomogram: Predicting non-organ confined stage of≥ pT3 in cT1 clear cell renal cell carcinoma

M Wenzel, B Hoeh, J Rührup, H Gambetta… - Frontiers in …, 2022 - frontiersin.org
Background Only one previously published study by Nocera et al. addressed the risk of
upstaging to≥ pT3 in cT1 clear cell renal cell carcinoma (ccRCC) by using characteristics of …

Contemporary seminal vesicle invasion rates in NCCN high‐risk prostate cancer patients

RS Flammia, B Hoeh, G Sorce, F Chierigo… - The …, 2022 - Wiley Online Library
Background Contemporary seminal vesicle invasion (SVI) rates in National Cancer
Comprehensive Network (NCCN) high‐risk prostate cancer (PCa) patients are not well …

External tertiary-care-hospital validation of the epidemiological SEER-based nomogram predicting downgrading in high-risk prostate cancer patients treated with …

C Cano Garcia, M Wenzel, ML Piccinelli, B Hoeh… - Diagnostics, 2023 - mdpi.com
We aimed to externally validate the SEER-based nomogram used to predict downgrading in
biopsied high-risk prostate cancer patients treated with radical prostatectomy (RP) in a …

The Dilemma of Misclassification Rates in Senior Patients With Prostate Cancer, Who Were Treated With Robot-Assisted Radical Prostatectomy: Implications for …

N Liakos, JH Witt, P Rachubinski… - Frontiers in …, 2022 - frontiersin.org
Objectives There is a recent paradigm shift to extend robot-assisted radical prostatectomy
(RARP) to very senior prostate cancer (PCa) patients based on biological fitness …

Grade group 4 prostate cancer without intraductal carcinoma on biopsy is more likely to be downgraded on prostatectomy than with intraductal carcinoma

L Trabzonlu, T Chaiprasit, A Kontosis, M Picken - Virchows Archiv, 2024 - Springer
In this study, we investigated the association between intraductal carcinoma of the prostate
(IDCP) along with several histopathological features on prostate biopsy and downgrading of …

The role of PSMA PET/CT in predicting downgrading in patients with Gleason score 4+ 4 prostate cancer in prostate biopsy

IC Aykanat, Y Kordan, H Seymen, E Koseoglu… - World Journal of …, 2024 - Springer
Background To investigate the predictable parameters associated with downgrading in
patients with a Gleason score (GS) 8 (4+ 4) in prostate biopsy after radical prostatectomy …

Influence of biopsy Gleason score on the risk of lymph node invasion in patients with intermediate-risk prostate cancer undergoing radical prostatectomy

M Wenzel, F Preisser, B Hoeh, MN Welte… - Frontiers in …, 2021 - frontiersin.org
Objective: To analyze the influence of biopsy Gleason score on the risk for lymph node
invasion (LNI) during pelvic lymph node dissection (PLND) in patients undergoing radical …