[HTML][HTML] From bacterial killing to immune modulation: Recent insights into the functions of lysozyme

SA Ragland, AK Criss - PLoS pathogens, 2017 - journals.plos.org
Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing
by lysozyme occurs through the hydrolysis of cell wall peptidoglycan (PG). Conventional …

[HTML][HTML] Lysozyme and its application as antibacterial agent in food industry

N Nawaz, S Wen, F Wang, S Nawaz, J Raza, M Iftikhar… - Molecules, 2022 - mdpi.com
Lysozymes are hydrolytic enzymes characterized by their ability to cleave the β-(1, 4)-
glycosidic bonds in peptidoglycan, a major structural component of the bacterial cell wall …

[HTML][HTML] Bacterial cell wall structure and dynamics

T Dörr, PJ Moynihan, C Mayer - Frontiers in microbiology, 2019 - frontiersin.org
The bacterial cell wall is a complex, mesh-like structure that in most bacteria is essential for
maintenance of cell shape and structural integrity. Historically, the cell wall has been of …

[HTML][HTML] Recent insights into the prognostic and therapeutic applications of lysozymes

L Jiang, Y Li, L Wang, J Guo, W Liu, G Meng… - Frontiers in …, 2021 - frontiersin.org
Lysozymes are naturally occurring enzymes present in a variety of biological organisms,
such as bacteria, fungi, and animal bodily secretions and tissues. It is also the main …

Modifications to the peptidoglycan backbone help bacteria to establish infection

KM Davis, JN Weiser - Infection and immunity, 2011 - Am Soc Microbiol
Bacterial pathogens that colonize mucosal surfaces have acquired resistance to
antimicrobials that are abundant at these sites. One of the main antimicrobials present on …

[HTML][HTML] Bacterial strategies to preserve cell wall integrity against environmental threats

AK Yadav, A Espaillat, F Cava - Frontiers in microbiology, 2018 - frontiersin.org
Bacterial cells are surrounded by an exoskeleton-like structure, the cell wall, composed
primarily of the peptidoglycan (PG) sacculus. This structure is made up of glycan strands …

[HTML][HTML] Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions

V Sukhithasri, N Nisha, L Biswas, VA Kumar… - Microbiological …, 2013 - Elsevier
The innate immune system constitutes the first line of defence against invading microbes.
The basis of this defence resides in the recognition of defined structural motifs of the …

[HTML][HTML] Structural variations of the cell wall precursor lipid II in Gram-positive bacteria—Impact on binding and efficacy of antimicrobial peptides

D Münch, HG Sahl - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2015 - Elsevier
Antimicrobial peptides (AMPs) are natural antibiotics produced by virtually all living
organisms. Typically, AMPs are cationic and amphiphilic and first contacts with target …

Peptidoglycan

M Pazos, K Peters - Bacterial cell walls and membranes, 2019 - Springer
The peptidoglycan sacculus is a net-like polymer that surrounds the cytoplasmic membrane
in most bacteria. It is essential to maintain the bacterial cell shape and protect from turgor …

A bacterial siren song: intimate interactions between Neisseria and neutrophils

AK Criss, HS Seifert - Nature Reviews Microbiology, 2012 - nature.com
Neisseria gonorrhoeae and Neisseria meningitidis are Gram-negative bacterial pathogens
that are exquisitely adapted for growth at human mucosal surfaces and for efficient …