Understanding the cellular and molecular mechanisms underlying the formation and
maintenance of memories is a central goal of the neuroscience community. It is well …

It is humbling to think that 30 years have passed since the paper by Collingridge, Kehl and
McLennan showing that one of Jeff Watkins most interesting compounds, R-2-amino-5 …

The hippocampus is assumed to retrieve memory by reinstating patterns of cortical activity
that were observed during learning. To test this idea, we monitored the activity of individual …

Mutations that cause intellectual disability (ID) and autism spectrum disorder (ASD) are
commonly found in genes that encode for synaptic proteins. However, it remains unclear …

Background Episodic memories are encoded within hippocampal and neocortical circuits.
Retrieving these memories is assumed to involve reactivation of neural ensembles that were …

Memory allows organisms to predict future events based on prior experiences. This requires
encoded information to persist once important predictors are extracted, while also being …

A more complete understanding of how fear extinction alters neuronal activity and
connectivity within fear circuits may aid in the development of strategies to treat human fear …

Memory formation is dynamic in nature, and acquisition of new information is often
influenced by previous experiences. Memories sharing certain attributes are known to …

The neuroendocrine response to episodes of acute stress is crucial for survival whereas the
prolonged response to chronic stress can be detrimental. Learning and memory are …

Learning and memory are basic functions of the brain that allowed human evolution. It is
well accepted that during learning and memory formation the dynamic establishment of new …