Hepatitis B virus biology and life cycle
S Tsukuda, K Watashi - Antiviral research, 2020 - Elsevier
Hepatitis B virus (HBV) specifically infects hepatocytes and causes severe liver diseases.
The HBV life cycle is unique in that the genomic DNA (relaxed-circular partially double …
The HBV life cycle is unique in that the genomic DNA (relaxed-circular partially double …
All about the RNA: interferon-stimulated genes that interfere with viral RNA processes
E Yang, MMH Li - Frontiers in immunology, 2020 - frontiersin.org
Interferon (IFN) signaling induces the expression of a wide array of genes, collectively
referred to as IFN-stimulated genes (ISGs) that generally function to inhibit viral replication …
referred to as IFN-stimulated genes (ISGs) that generally function to inhibit viral replication …
[PDF][PDF] Serum hepatitis B virus RNA: a new potential biomarker for chronic hepatitis B virus infection
S Liu, B Zhou, JD Valdes, J Sun, H Guo - Hepatology, 2019 - Wiley Online Library
Chronic hepatitis B infection is one of the major etiological causes of liver failure, cirrhosis,
and hepatocellular carcinoma (HCC) worldwide. This condition cannot be completely cured …
and hepatocellular carcinoma (HCC) worldwide. This condition cannot be completely cured …
Revisiting hepatitis B virus: challenges of curative therapies
With a yearly death toll of 880,000, hepatitis B virus (HBV) remains a major health problem
worldwide, despite an effective prophylactic vaccine and well-tolerated, effective antivirals …
worldwide, despite an effective prophylactic vaccine and well-tolerated, effective antivirals …
Pathogenicity and virulence of Hepatitis B virus
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …
an estimated 296 million people in the world that are chronically infected by this virus, and …
Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts
Interferon (IFN) stimulates a whole repertoire of cellular genes, collectively referred to as
ISGs (Interferon-stimulated genes). ISG20, a 3´-5´ exonuclease enzyme, has been …
ISGs (Interferon-stimulated genes). ISG20, a 3´-5´ exonuclease enzyme, has been …
HBV‐induced increased N6 methyladenosine modification of PTEN RNA affects innate immunity and contributes to HCC
Background and Aims Epitranscriptomic modification of RNA has emerged as the most
prevalent form of regulation of gene expression that affects development, differentiation …
prevalent form of regulation of gene expression that affects development, differentiation …
[HTML][HTML] HBV bypasses the innate immune response and does not protect HCV from antiviral activity of interferon
Background & Aims Hepatitis C virus (HCV) infection is sensitive to interferon (IFN)-based
therapy, whereas hepatitis B virus (HBV) infection is not. It is unclear whether HBV escapes …
therapy, whereas hepatitis B virus (HBV) infection is not. It is unclear whether HBV escapes …
Interferon and hepatitis B: current and future perspectives
J Ye, J Chen - Frontiers in Immunology, 2021 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …
Mechanisms of immune regulation by the placenta: Role of type I interferon and interferon‐stimulated genes signaling during pregnancy
Pregnancy is a unique condition where the maternal immune system is continuously
adapting in response to the stages of fetal development and signals from the environment …
adapting in response to the stages of fetal development and signals from the environment …