Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …

Monocytes and macrophages are central players of the innate immune response and play a
pivotal role in the regulation of inflammation. Thereby, they actively participate in all phases …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Various lung insults can result in replacement of resident alveolar macrophages (AM) by
bone marrow monocyte–derived (BMo)–AM. However, the dynamics of this process and its …

With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post …

Type I interferons (IFN-I) are critical mediators of innate control of viral infections but also
drive the recruitment of inflammatory cells to sites of infection, a key feature of severe …

Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease
caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on …

Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …

The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …