In vitro models of biological barriers for nanomedical research

F Carton, M Malatesta - International Journal of Molecular Sciences, 2022 - mdpi.com
Nanoconstructs developed for biomedical purposes must overcome diverse biological
barriers before reaching the target where playing their therapeutic or diagnostic function. In …

Nanomedicine for drug delivery throughout the alimentary canal

B Cote, D Rao, AWG Alani - Molecular Pharmaceutics, 2021 - ACS Publications
The field of nanomedicine continues to grow with new technologies and formulations in
development for several disease states. Much research focuses on the use of injectable …

Formulation, characterization and biological activity screening of sodium alginate-gum arabic nanoparticles loaded with curcumin

A Hassani, S Mahmood, HH Enezei, SA Hussain… - Molecules, 2020 - mdpi.com
The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle,
offering the optional property of delivering drugs as a single dose rather than in multiple …

Zein-based nanoparticles for the oral delivery of insulin

L Inchaurraga, AL Martínez-López… - Drug Delivery and …, 2020 - Springer
The aim of this work was to evaluate oral nanocarriers, prepared from zein nanoparticles
coated with a poly (anhydride)-thiamine conjugate (GT), for the delivery of insulin …

A green and fast microwave-assisted synthesis of selenium nanoparticles and their characterization under gastrointestinal conditions using mass spectrometry

M Borowska, J Jiménez-Lamana, K Bierla, K Jankowski… - Food Chemistry, 2023 - Elsevier
We present a novel microwave-assisted green synthesis of selenium nanoparticles (SeNPs)
using yeast extract as source of a non-toxic reducing and capping agents. Effects of …

[HTML][HTML] In vivo testing of mucus-permeating nanoparticles for oral insulin delivery using Caenorhabditis elegans as a model under hyperglycemic conditions

AL Martínez-López, CJ González-Navarro… - … Pharmaceutica Sinica B, 2021 - Elsevier
The aim was to evaluate the potential of mucus-permeating nanoparticles for the oral
administration of insulin. These nanocarriers, based on the coating of zein nanoparticles …

Cytotoxicity and bioavailability assessment from thiamin-phospholipid complexation loaded Ajwain oil based self nanoemulsifying system

A Kumar, A Jindal, PK Singh Arya - Journal of Dispersion Science …, 2023 - Taylor & Francis
Abstract Poor bioavailability (< 5%) of thiamin hydrochloride (TH) primarily relates to its
impaired permeability across gut mucosa. To modulate its permeability, a dual system based …

Pharmacokinetics of vitamin dosage forms: A complete overview

VV Sugandhi, R Pangeni, LK Vora… - Food Science & …, 2024 - Wiley Online Library
Vitamins are crucial for sustaining life because they play an essential role in numerous
physiological processes. Vitamin deficiencies can lead to a wide range of severe health …

[HTML][HTML] Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate

L Inchaurraga, AL Martínez-López… - International Journal of …, 2019 - Elsevier
The aim of this work was to evaluate the mucus-permeating properties of nanocarriers using
zein nanoparticles (NPZ) coated with a Gantrez® AN-thiamine conjugate (GT). NPZ were …

Zein-based nanocarriers for the oral delivery of insulin. In vivo evaluation in Caenorhabditis elegans

AL Martínez-López, CJ González-Navarro… - Drug Delivery and …, 2021 - Springer
The aim was to evaluate the potential of nanocarriers, based on the coating of zein
nanoparticles (ZNP) with a Gantrez® AN-PEG conjugate (GP), for the oral delivery of insulin …