Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs
in an undetectable and asymptomatic state for many years. These lesions do not progress in …

Considerable evidence supports the effectiveness of aspirin for chemoprevention of
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …

Heme oxygenase-1, an enzyme degrading heme to carbon monoxide, iron, and biliverdin,
has been recognized as playing a crucial role in cellular defense against stressful …

Evidence from a wide range of sources suggests that individuals taking aspirin and related
non-steroidal anti-inflammatory drugs have reduced risk of large bowel cancer. Work in …

Evidence supporting aspirin and resistant starch (RS) for colorectal cancer prevention
comes from epidemiologic and laboratory studies (aspirin and RS) and randomized …

The so-called reactive oxygen species (ROS) are defined as oxygen-containing species that
are more reactive than O 2 itself, which include hydrogen peroxide and superoxide …

Preeclampsia is an inflammatory disease with endothelial cell dysfunction that occurs via
decreased endothelial nitric oxide synthase/nitric oxide (eNOS/NO) activity. Aspirin reduces …

Acetylsalicylic acid (aspirin) is highly effective for treating colon cancer patients
postdiagnosis; however, the mechanisms of action of aspirin in colon cancer are not well …

Aspirin inhibits the enzyme cyclooxygenase (Cox), and there is a significant body of
epidemiological evidence demonstrating that regular aspirin use is associated with a …

Objective: Patients with psoriasis have impaired vascular health and increased
cardiovascular disease (CVD). Platelets are key players in the pathogenesis of vascular …