The dental plaque biofilm matrix

NS Jakubovics, SD Goodman… - Periodontology …, 2021 - Wiley Online Library
The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Host response mechanisms in periodontal diseases

N Silva, L Abusleme, D Bravo, N Dutzan… - Journal of Applied Oral …, 2015 - SciELO Brasil
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis
and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm …

Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen

N Bostanci, GN Belibasakis - FEMS microbiology letters, 2012 - academic.oup.com
Porphyromonas gingivalis is a Gram-negative oral anaerobe that is involved in the
pathogenesis of periodontitis, an inflammatory disease that destroys the tissues supporting …

Porphyromonas gingivalis Virulence Factors and Clinical Significance in Periodontal Disease and Coronary Artery Diseases

LH Aleksijević, M Aleksijević, I Škrlec, M Šram, M Šram… - Pathogens, 2022 - mdpi.com
Porphyromonas gingivalis is a gram-negative, anaerobic bacterium that lives in the oral
cavity. It is an integral part of the oral microbiome, which includes more than 500 types of …

Host-pathogen interactions in progressive chronic periodontitis

M Hernández, N Dutzan… - Journal of dental …, 2011 - journals.sagepub.com
Periodontitis is an infection characterized by the occurrence of supporting tissue destruction
with an episodic nature. Disease progression is often determined by the loss of attachment …

Alzheimer's Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats Is Serotype Dependent

J Díaz-Zúñiga, J More, S Melgar-Rodríguez… - Frontiers in …, 2020 - frontiersin.org
Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with
inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota …

Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis

NM Moutsopoulos, HM Kling, N Angelov, W Jin… - Journal of …, 2012 - Elsevier
In periodontitis, a common chronic inflammatory condition, gram-negative-rich bacterial
biofilms trigger, in susceptible individuals, perpetuating inflammation that results in …

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

KQ De Andrade, CLC Almeida-da-Silva… - Mediators of …, 2019 - Wiley Online Library
Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) are
Gram‐negative anaerobic bacteria possessing several virulence factors that make them …

The capsule of Porphyromonas gingivalis leads to a reduction in the host inflammatory response, evasion of phagocytosis, and increase in virulence

A Singh, T Wyant, C Anaya-Bergman… - Infection and …, 2011 - Am Soc Microbiol
Periodontal disease is a chronic oral inflammatory disease that is triggered by bacteria such
as Porphyromonas gingivalis. P. gingivalis strains exhibit great heterogeneity, with some …