One in 4 Americans> 40 years of age takes a statin to reduce the risk of myocardial
infarction, ischemic stroke, and other complications of atherosclerotic disease. The most …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Aims To objectively appraise evidence for possible adverse effects of long-term statin
therapy on glucose homeostasis, cognitive, renal and hepatic function, and risk for …

Hydroxy-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors or statins are well
tolerated, but associated with various statin-associated symptoms (SAS), including statin …

Background Hydroxymethyl glutaryl coenzyme A reductase inhibitors, commonly called
statins, are some of the most commonly prescribed medications worldwide. Evidence …

Acute kidney injury (AKI) is a widespread problem of epidemic status. Compelling evidence
indicates that the incidence of AKI is rapidly increasing, particularly among hospitalized …

Acute kidney injury (AKI), once viewed predominantly as a self-limited and reversible
condition, is now recognized as a growing problem associated with significant risks of …

This Review is intended to help clinicians, patients, and the public make informed decisions
about statin therapy for the prevention of heart attacks and strokes. It explains how the …

Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …

Acute kidney injury (AKI), previously termed acute renal failure, is associated with increased
mortality, prolonged hospital stay, and accelerated chronic kidney disease (CKD). Over the …