The global obesity epidemic is a major contributor to chronic disease and disability in the
world today. Since the discovery of leptin in 1994, a multitude of studies have characterized …

Excess body weight is associated not only with an increased risk of type 2 diabetes and
cardiovascular disease (CVD) but also with various types of malignancies. Adiponectin, the …

Obesity is characterized by chronic systemic inflammation and enhances cancer metastasis
and mortality. Obesity promotes breast cancer metastasis to lung in a neutrophil-dependent …

De wederkerigheidsregel schrijft ons voor dat we teruggeven wat we krijgen. Dit is een
logische sociale regel die er voor zorgt dat de drempel om als eerste iets te geven, zo laag …

There has been much effort recently to define the role of adipocytokines, which are soluble
mediators derived mainly from adipocytes (fat cells), in the interaction between adipose …

Obesity represents a risk factor for development of insulin resistance and type 2 diabetes. In
addition, it has been associated with increased adipocyte formation in the bone marrow …

Adipocytes were identified in human bone marrow more than a century ago, yet until
recently little has been known about their origin, development, function or interactions with …

Adiponectin has until now been considered to be synthesized and secreted exclusively by
the adipose tissue, and is reported to influence energy homeostasis and insulin sensitivity. It …

Ceretain treatments may lead to significant changes in adipocytokine levels. For example
include beta-2 adrenoreceptor agonists, thiazolidinediones as well as androgens lead to …

Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its
involvement in obesity-related disorders such as insulin resistance, type 2 diabetes mellitus …