Kidney stones

SR Khan, MS Pearle, WG Robertson… - Nature reviews Disease …, 2016 - nature.com
Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are …

Idiopathic hypercalciuria and formation of calcium renal stones

FL Coe, EM Worcester, AP Evan - Nature Reviews Nephrology, 2016 - nature.com
The most common presentation of nephrolithiasis is idiopathic calcium stones in patients
without systemic disease. Most stones are primarily composed of calcium oxalate and form …

Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement

G Gambaro, E Croppi, F Coe, J Lingeman, O Moe… - Journal of …, 2016 - Springer
Background Recently published guidelines on the medical management of renal stone
disease did not address relevant topics in the field of idiopathic calcium nephrolithiasis …

Protective roles of flavonoids and flavonoid-rich plant extracts against urolithiasis: A review

X Zeng, Y Xi, W Jiang - Critical reviews in food science and …, 2019 - Taylor & Francis
In the urinary system, urolithiasis is the third prevalent disorder which causes severe pain in
individuals. Urinary stones are composed of calcium oxalate (CaOx) and calcium phosphate …

[HTML][HTML] The association between bacteria and urinary stones

AL Schwaderer, AJ Wolfe - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
Urinary stone disease (USD) is an increasing clinical problem in both children and adults.
One in ten individuals will experience a urinary stone, yet the mechanisms responsible for …

The interaction between Enterobacteriaceae and calcium oxalate deposits

E Barr-Beare, V Saxena, EE Hilt, K Thomas-White… - PloS one, 2015 - journals.plos.org
Background The role of calcium oxalate crystals and deposits in UTI pathogenesis has not
been established. The objectives of this study were to identify bacteria present in pediatric …

Genome-wide gene expression profiling of Randall's plaques in calcium oxalate stone formers

K Taguchi, S Hamamoto, A Okada… - Journal of the …, 2017 - journals.lww.com
Randall plaques (RPs) can contribute to the formation of idiopathic calcium oxalate (CaOx)
kidney stones; however, genes related to RP formation have not been identified. We …

Geobiology reveals how human kidney stones dissolve in vivo

M Sivaguru, JJ Saw, JC Williams Jr, JC Lieske… - Scientific Reports, 2018 - nature.com
More than 10% of the global human population is now afflicted with kidney stones, which are
commonly associated with other significant health problems including diabetes …

The renal pelvis urobiome in the unilateral kidney stone patients revealed by 2bRAD-M

SY Hong, YY Yang, JZ Xu, QD Xia, SG Wang… - Journal of Translational …, 2022 - Springer
Background The pathogenesis of kidney stone disease (KSD) is not fully understood, and
potential contributing factors remain to be explored. Several studies have revealed that the …

[HTML][HTML] Probiotics for prevention of urinary stones

JC Lieske - Annals of Translational Medicine, 2017 - ncbi.nlm.nih.gov
Background Urinary supersaturation is one key determinant of calcium oxalate (CaOx)
urinary stone formation, and urinary excretions of oxalate and citrate are two key …