This review provides an overview of the clinical issue of poorly controlled postoperative pain
and therapeutic approaches that may help to address this common unresolved health-care …

The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …

Introduction Worldwide, more than 20 million patients undergo groin hernia repair annually.
The many different approaches, treatment indications and a significant array of techniques …

Effective prevention of chronic postoperative pain is an important clinical goal, informed by a
growing body of studies. Peri‐operative regional anaesthesia remains one of the most …

Background: The pathophysiology of pain involves complex nervous system interactions
after initial noxious stimuli. When stimuli persist, biochemical and structural changes occur in …

Objectives: Anxiety and pain catastrophizing predict acute postoperative pain. However, it is
not well established whether they also predict chronic postsurgical pain (CPSP). The aim of …

The transition from acute to chronic pain appears to occur in discrete pathophysiological and
histopathological steps. Stimuli initiating a nociceptive response vary, but receptors and …

Most patients who undergo surgery recover uneventfully and resume their normal daily
activities within weeks. Nevertheless, chronic postsurgical pain develops in an alarming …

In the past ten years there has been recognition that chronic post-surgical pain is a
significant problem. This is a complex area of research and although the quality of studies …

Background and objectives Optimism is a personality trait which has repeatedly been shown
to correlate with, and predict psychological and physical well-being. The present study …