Understanding the physiology of human defaecation and disorders of continence and evacuation

PT Heitmann, PF Vollebregt, CH Knowles… - Nature reviews …, 2021 - nature.com
The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Epidemiology of constipation in children and adults: a systematic review

SM Mugie, MA Benninga, C Di Lorenzo - Best practice & research Clinical …, 2011 - Elsevier
We aimed to review the published literature regarding the epidemiology of constipation in
the general paediatric and adult population and to assess its geographic, gender and age …

Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies

A Flint, A Raben, JE Blundell, A Astrup - International journal of obesity, 2000 - nature.com
OBJECTIVE: To examine reproducibility and validity of visual analogue scales (VAS) for
measurement of appetite sensations, with and without a diet standardization prior to the test …

Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status

J Mayneris-Perxachs, M Arnoriaga-Rodríguez… - Microbiome, 2020 - Springer
Background Gonadal steroid hormones have been suggested as the underlying mechanism
responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have …

Sex differences in pain

KJ Berkley - Behavioral and Brain Sciences, 1997 - cambridge.org
Are there sex differences in pain? For experimentally delivered somatic stimuli, females
have lower thresholds, greater ability to discriminate, higher pain ratings, and less tolerance …

You've got male: Sex and the microbiota-gut-brain axis across the lifespan

M Jaggar, K Rea, S Spichak, TG Dinan… - Frontiers in …, 2020 - Elsevier
Sex is a critical factor in the diagnosis and development of a number of mental health
disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease …

Basic anatomical and physiological data for use in radiological protection: reference values: ICRP Publication 89

J Valentin - Annals of the ICRP, 2002 - Elsevier
This report presents detailed information on age-and gender-related differences in the
anatomical and physiological characteristics of reference individuals. These reference …

Gastroretentive technologies in tandem with controlled-release strategies: A potent answer to oral drug bioavailability and patient compliance implications

NN Vrettos, CJ Roberts, Z Zhu - Pharmaceutics, 2021 - mdpi.com
There have been many efforts to improve oral drug bioavailability and therapeutic efficacy
and patient compliance. A variety of controlled-release oral delivery systems have been …

The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006

HK Jung, GR Locke III, CD Schleck, AR Zinsmeister… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The epidemiology of gastroparesis is unknown. We aimed to
determine the incidence, prevalence, and outcome of gastroparesis in the community …

Biological basis of sex differences in drug abuse: preclinical and clinical studies

WJ Lynch, ME Roth, ME Carroll - Psychopharmacology, 2002 - Springer
The recent focus on drug abuse in women has brought attention to numerous differences
between women and men. In this review, we discuss both preclinical and clinical findings of …